Autoimmune Hepatitis with Concomitant Idiopathic Thrombocytopenic Purpura Diagnosed by Transjugular Liver Biopsy.

Authors:
Hiromi Fukuda
Hiromi Fukuda
Oita University of Nursing and Health Sciences
Kazuhide Takata
Kazuhide Takata
Fukuoka University
Ryo Yamauchi
Ryo Yamauchi
Gifu University
Japan
Hideo Kunimoto
Hideo Kunimoto
Hakujyuji Hospital Department of Hepatology
Japan
Takashi Tanaka
Takashi Tanaka
Institute of Natural Medicine
Japan
Keiji Yokoyama
Keiji Yokoyama
Fukuoka University Faculty of Medicine
Daisuke Morihara
Daisuke Morihara
Fukuoka University Faculty of Medicine
Japan

Case Reports Hepatol 2018 9;2018:5305691. Epub 2018 Dec 9.

Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan, Fukuoka 814-0180, Japan.

Patients with autoimmune hepatitis (AIH) may sometimes have concomitant idiopathic thrombocytopenic purpura (ITP). Severe thrombocytopenia in ITP interferes with percutaneous liver biopsy for pathological diagnosis of AIH. Here, we report a case of AIH with ITP in a 63-year-old woman. The patient presented to our hospital with liver dysfunction and thrombocytopenia. For histological examination, transjugular liver biopsy (TJLB) was performed, leading to a diagnosis of AIH. Corticosteroids treatment led to an improvement in her liver enzyme levels and platelet count. In conclusion, patients with AIH may sometimes have concomitant ITP. TJLB was effective for making the diagnosis of AIH with severe thrombocytopenia due to ITP.

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Source
https://www.hindawi.com/journals/crihep/2018/5305691/
Publisher Site
http://dx.doi.org/10.1155/2018/5305691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304620PMC
December 2018
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