Transpl Infect Dis 2019 Apr 11;21(2):e13045. Epub 2019 Jan 11.
Department of Anatomical Pathology, Alfred Health, Melbourne, Victoria, Australia.
Parvovirus B19 (PB19) associated pure red cell aplasia (PRCA) is an uncommon but well described complication of immunosuppression post solid organ transplantation. We report a unique case of a renal transplant patient with PB19 associated PRCA who developed a spontaneous splenic rupture after receiving IVIg for persistent anemia. He subsequently required splenectomy. Within the spleen we subsequently identified PB19 affected cells.