Hybrid operation to revascularize long-segment occluded internal carotid artery prevent further ischemic events.

Authors:
Kun Zhang
Kun Zhang
College of Life Sciences
China
Ying-Kun He
Ying-Kun He
School of Environmental Science and Engineering
Chapel Hill | United States
Bo-Wen Yang
Bo-Wen Yang
First Affiliated Hospital

Neuroradiology 2019 Feb 14;61(2):217-224. Epub 2018 Dec 14.

Henan Provincial People's Hospital, Zhengzhou University, 7 Weiwu Road, Zhengzhou, 450003, Henan Province, China.

Purpose: The effects and complications of hybrid procedure (combined carotid endarterectomy and carotid stenting) to revascularize chronic long-segment occlusion of internal carotid artery (ICA) are currently unknown and the purpose of this study.

Methods: Sixty-five patients with long-segment occlusion of ICA were prospectively enrolled and divided into two groups of revascularization with hybrid operation (n = 30) and medication group (n = 35), and clinical and angiographic data were analyzed.

Results: The duration from symptom onset to revascularization ranged 17-120 days (mean 40.5 ± 5.0) in the hybrid operation, with a success revascularization rate of 100%. All patients had thrombi extracted with the clot length ranging 5-8 cm (mean 6.3 ± 0.9). The thrombolysis in cerebral infarction grade (TICI) was significantly (P < 0.0001) greater immediately after (median 2,) than before recanalization (0). Periprocedural complications included recurrent laryngeal nerve injury in one patient and intracranial hemorrhage in another (6.7%), but no severe neurological deficits occurred. The symptoms were significantly (P < 0.0001) improved after compared with before operation, with the modified Rankin score of 2.5 ± 0.6 at 3 months postoperation which was significantly (P < 0.0001) improved compared with before revascularization (3.4 ± 0.6). Follow-up angiography revealed patent ICA in all patients with hybrid operation. In the medication alone group, no significant (P > 0.05) improvement was observed with the mRS score of 3.5 ± 0.8 at admission and 3.4 ± 0.7 at 3 months, which was significantly (P < 0.001) greater than in the hybrid operation.

Conclusion: Hybrid operation may be safe and effective in revascularizing long-segment occlusion of internal carotid artery for prevention of further ischemic events.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00234-018-2145-7DOI Listing

Still can't find the full text of the article?

We can help you send a request to the authors directly.
February 2019
2.485 Impact Factor

Article Mentions


Provided by Crossref Event Data
twitter
Twitter: IllingworthInfo
December 14, 2018, 3:34 am EST

Publication Analysis

Top Keywords

hybrid operation
12
carotid artery
8
long-segment occlusion
8
internal carotid
8
purpose studymethods
4
ranged 17-120 days
4
revascularization ranged
4
onset revascularization
4
patients long-segment
4
sixty-five patients
4
unknown purpose
4
studymethods sixty-five
4
currently unknown
4
operation success
4
occlusion internal
4
success revascularization
4
artery ica
4
405 ± 50 hybrid
4
17-120 days 405 ± 50
4
ica currently
4

References

(Supplied by CrossRef)
Article in AJNR Am J Neuroradiol
S Endo et al.
AJNR Am J Neuroradiol 1998
Article in J Vasc Surg
GC Kasper et al.
J Vasc Surg 2001
Article in Neurosurgery
M Komiyama et al.
Neurosurgery 1994
Article in Surg Neurol
M Komiyama et al.
Surg Neurol 2006
Article in J Stroke
YJ Bae et al.
J Stroke 1966
Article in Neurology
J Balow et al.
Neurology 1966
Article in J Neuroimaging
A Bhatt et al.
J Neuroimaging 2009
Article in Neurosurgery
ES Nussbaum et al.
Neurosurgery 2000
Article in J Gastroenterol Hepatol
CL Lin et al.
J Gastroenterol Hepatol 2007
Article in World J Radiol
JH Shin et al.
World J Radiol 2010
Article in Int J Clin Exp Pathol
L Zhang et al.
Int J Clin Exp Pathol 2014

Similar Publications