Pubfacts - Scientific Publication Data
  • Categories
  • Journals
  • ->
  • Login
  • Categories
  • Journals

Search Our Scientific Publications & Authors

Publications
  • Publications
  • Authors
find publications by category +
Translate page:

Three-dimensional mitral valve structure in predicting moderate ischemic mitral regurgitation improvement after coronary artery bypass grafting.

Authors:
Xiaotian Sun Yuwen Jiang Guoqian Huang Jiechun Huang Meng Shi Liewen Pang Yiqing Wang

J Thorac Cardiovasc Surg 2019 05 29;157(5):1795-1803.e2. Epub 2018 Sep 29.

Department of Cardiothoracic Surgery, Huashan Hospital of Fudan University, Shanghai, China. Electronic address:

Objective: Focusing on 3-dimensional mitral valve structure, this study investigated predictors for moderate ischemic mitral regurgitation (IMR) improvement after off-pump coronary artery bypass grafting (OPCAB).

Methods: This study included 143 patients (age 67.6 ± 7.6 years, 32.9% female) with previous myocardial infarction and moderate IMR undergoing OPCAB. Preoperative 3-dimensional echocardiographic data were analyzed, focusing on mitral annular geometry and leaflet tethering model. Patients were grouped according to IMR at 1-year postoperative follow-up into improved (n = 65), with no or mild IMR, and failure (n = 70), with moderate or severe IMR, groups. Groups were compared to identify predictors of IMR improvement after OPCAB.

Results: Eight patients died within 1 year. At 1 postoperative year, improved group included 65 patients; failure group included 70. Improved group had less preoperative annular flattening (smaller nonplanar angle) and segmental leaflet tethering (smaller A3, P1, P2, and P3 tethering angles) than failure group. Nonplanar angle (P < .001) and P3 tethering angle (P < .001) were independent predictors of moderate IMR improvement after OPCAB. Receiver operator characteristic curves defined P3 tethering angle of 28.8° (sensitivity of 78.6%, specificity of 84.6%) and nonplanar angle of 158.1° (sensitivity, 64.3% and specificity of 86.2%) as the cutoff values.

Conclusions: Preoperative moderate IMR can be improved by OPCAB in selected patients. Less annular flattening and P3 leaflet tethering may predict improvement of moderate IMR after OPCAB, suggesting that the annular nonplanar saddle shape and less leaflet tethering toward P3 segment are important for the prognosis of moderate IMR.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtcvs.2018.09.018DOI Listing
May 2019

Publication Analysis

Top Keywords

leaflet tethering
8
mitral regurgitation
8
ischemic mitral
8
nonplanar angle
8
failure group
8
artery bypass
8
imr improvement
8
improved group
8
group included
8
bypass grafting
8
moderate ischemic
8
coronary artery
8
valve structure
8
mitral valve
8
imr
6
n = 65 mild
4
mild imr
4
improved n = 65
4
imr failure
4
follow-up improved
4

Similar Publications

Selection of the Optimal Candidate to MitraClip for Secondary Mitral Regurgitation: Beyond Mitral Valve Morphology.

Authors:
Tanya Salvatore Fabrizio Ricci George D Dangas Bushra S Rana Laura Ceriello Luca Testa Mohammed Y Khanji Anna Laura Caterino Corrado Fiore Antonio Popolo Rubbio Marianna Appignani Maria Di Fulvio Francesco Bedogni Sabina Gallina Marco Zimarino

Front Cardiovasc Med 2021 3;8:585415. Epub 2021 Feb 3.

Institute of Cardiology, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.

Secondary mitral regurgitation (MR) occurs despite structurally normal valve apparatus due to an underlying disease of the myocardium leading to disruption of the balance between tethering and closing forces with ensuing failure of leaflet coaptation. In patients with heart failure (HF) and left ventricular dysfunction, secondary MR is independently associated with poor outcome, yet prognostic benefits related to the correction of MR have remained elusive. Surgery is not recommended for the correction of secondary MR outside coronary artery bypass grafting. Read More

View Article and Full-Text PDF
February 2021
Similar Publications

Mitral Regurgitation in Patients With Coexisting Chronic Aortic Regurgitation: An Evidence-Based Narrative Review.

Authors:
Kinjal M Patel Ronak G Desai Sandeep Krishnan

J Cardiothorac Vasc Anesth 2021 Jan 8. Epub 2021 Jan 8.

Wayne State University School of Medicine, St. Joseph Mercy Oakland Medical Office Building, Pontiac, MI.

Chronic aortic regurgitation (AR) frequently leads to significant downstream changes to the left ventricle and pulmonary vasculature; these structural and physiologic changes result in lower- than expected patient survival. Progressive, uncorrected AR can lead to left ventricle dilation and subsequent mitral valve leaflet tethering, as well as mitral annular dilation, resulting in secondary mitral regurgitation (MR) in up to 45% of patients. Surgical aortic valve replacement (AVR) improves secondary MR in most patients, but survival is significantly lower in those patients who do not show improvement in MR after AVR. Read More

View Article and Full-Text PDF
January 2021
Similar Publications

Cardiac remodelling in secondary tricuspid regurgitation: Should we look beyond the tricuspid annulus diameter?

Authors:
Anne Guérin Elsa Vabret Julien Dreyfus Yoan Lavie-Badie Catherine Sportouch Jean-Christophe Eicher Sylvestre Maréchaux Thierry Le Tourneau Erwan Donal

Arch Cardiovasc Dis 2021 Jan 11. Epub 2021 Jan 11.

Université de Rennes 1, 35043 Rennes, France; Department of Cardiology, CHU Rennes, 35000 Rennes, France. Electronic address:

Background: A better understanding of the mechanism of tricuspid regurgitation severity would help to improve the management of this disease.

Aim: We sought to characterize the determinants of isolated secondary tricuspid regurgitation severity in patients with preserved left ventricular ejection fraction.

Methods: This was a prospective observational multicentre study. Read More

View Article and Full-Text PDF
January 2021
Similar Publications

Cardiovascular magnetic resonance reference values of mitral and tricuspid annular dimensions: the UK Biobank cohort.

Authors:
Fabrizio Ricci Nay Aung Sabina Gallina Filip Zemrak Kenneth Fung Giandomenico Bisaccia Jose Miguel Paiva Mohammed Y Khanji Cesare Mantini Stefano Palermi Aaron M Lee Stefan K Piechnik Stefan Neubauer Steffen E Petersen

J Cardiovasc Magn Reson 2020 Dec 17;23(1). Epub 2020 Dec 17.

William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.

Background: Mitral valve (MV) and tricuspid valve (TV) apparatus geometry are essential to define mechanisms and etiologies of regurgitation and to inform surgical or transcatheter interventions. Given the increasing use of cardiovascular magnetic resonance (CMR) for the evaluation of valvular heart disease, we aimed to establish CMR-derived age- and sex-specific reference values for mitral annular (MA) and tricuspid annular (TA) dimensions and tethering indices derived from truly healthy Caucasian adults.

Methods: 5065 consecutive UK Biobank participants underwent CMR using cine balanced steady-state free precession imaging at 1. Read More

View Article and Full-Text PDF
December 2020
Similar Publications

Surgical repair of ischemic mitral regurgitation: one ring does not fit all.

Authors:
Therese Servito Malak Elbatarny Bobby Yanagawa Aleksander Dokollari Gianluigi Bisleri

Curr Opin Cardiol 2021 Mar;36(2):154-162

Cardiac Surgery Innovation Lab, Queen's University, Kingston.

Purpose Of Review: The review summarizes the key parameters that can aid in determining the optimal treatment of ischemic mitral regurgitation (IMR).

Recent Findings: Left ventricular (LV) and mitral valve (MV) parameters are important for surgical planning and risk stratification in IMR. Although LV dimensions is one of the main parameters used in the guidelines, volumes more accurately depict LV remodelling. Read More

View Article and Full-Text PDF
March 2021
Similar Publications
Save 15% Survey
© 2021 PubFacts.
  • About PubFacts
  • Privacy Policy
  • Sitemap