Renal Dysfunction among Ghanaians Living with Clinically Diagnosed Hypertension in the Asutifi-South District: A Cross-Sectional Descriptive Study at the St. Elizabeth Hospital, Hwidiem.

Authors:
Mr James Osei-Yeboah, .MPhil
Mr James Osei-Yeboah, .MPhil
University of Health and Allied Sciences
Lecturer
Ho, Volta | Ghana
Sylvester Yao Lokpo
Sylvester Yao Lokpo
University of Health and Allied Sciences
Assistant Lecturer
Metabolic and infectious disease epidemiology
Ho, Volta Region | Ghana

Int J Hypertens 2018 5;2018:8428063. Epub 2018 Nov 5.

Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana.

Background: This study aimed at evaluating the burden of renal dysfunction among people living with hypertension in the Asutifi-South District of the Brong Ahafo Region, who were attending clinic at the St. Elizabeth Hospital in Hwidiem.

Methodology: A hospital-based, cross-sectional study was conducted among two hundred (200) hypertensive clients aged between 27 and 88 years who reported for clinical management from January to March, 2018. Data on sociodemography, comorbid disease status, antihypertensive medication, and their duration was obtained using a semistructured questionnaire and patient folders. Blood pressure, weight, and creatinine were measured using standard methods. Kidney function was assessed using Cockcroft Gault (CG), Four-Variable Modification of Diet in Renal Disease (4v-MDRD) and the Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equations. The 2012 Kidney Disease Improvement Global Outcome (KDIGO) Criteria were used to categorize renal function among study participants.

Results: Renal impairment was observed among 25.00%, 9.50%, and 10.50% of study participants using CG, 4v-MDRD, and CKD-EPI equations, respectively. With the exception of CKD-EPI equation, females significantly recorded higher scores compared to their male counterparts (28.95% vs 12.5%, 11.84%, vs 2.08%) using CG and 4v-MDRD, respectively. Participants aged 50 years or more recorded the highest renal impairment.

Conclusion: Renal dysfunction is common among people living with hypertension in the Asutifi-South District of the Brong Ahafo Region. Femininity, older age, disease comorbidity with diabetes, Thiazide diuretic and AR Blocker usage, and increasing duration of medication accounted for higher kidney dysfunction. Regular screening and management are therefore recommended to avert progression to end-stage renal failure (ESRD).

Download full-text PDF

Source
https://www.hindawi.com/journals/ijhy/2018/8428063/
Publisher Site
http://dx.doi.org/10.1155/2018/8428063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241342PMC
November 2018
32 Reads

Publication Analysis

Top Keywords

asutifi-south district
12
hypertension asutifi-south
12
renal dysfunction
12
renal
8
aged years
8
district brong
8
living hypertension
8
ckd-epi equations
8
elizabeth hospital
8
people living
8
ahafo region
8
brong ahafo
8
study
5
renal function
4
4v-mdrd ckd-epi
4
function study
4
categorize renal
4
equations exception
4
global outcome
4
outcome kdigo
4

References

(Supplied by CrossRef)

A Systematic Review and Meta-Analysis 2014

Journal of Marketing Research 2017

World Journal of Emergency Medicine 2014

Canadian Journal of Kidney Health and Disease 2015

Similar Publications