Emergence of staphylococcal scalded skin syndrome associated with a new toxinogenic, methicillin-susceptible Staphylococcus aureus clone.

Authors:
Anastassios Doudoulakakis
Anastassios Doudoulakakis
'P&A Kyriakou' Children's Hospital
Iris Spiliopoulou
Iris Spiliopoulou
University of Patras
Greece
Garyfallia Syridou
Garyfallia Syridou
Medical School
Nikolaos Giormezis
Nikolaos Giormezis
University of Patras
Greece
Maria Militsopoulou
Maria Militsopoulou
Laboratory of Biochemistry
Madison | United States
Evangelia Lebessi
Evangelia Lebessi
"P. & A. Kyriakou" Children's Hospital
Maria Tsolia
Maria Tsolia
University of Athens
Greece

J Med Microbiol 2019 Jan 12;68(1):48-51. Epub 2018 Nov 12.

4‚Äč2nd Department of Paediatrics, School of Medicine, National and Kapodistrian University of Athens, Greece.

A sharp increase in staphylococcal scalded skin syndrome (SSSS) cases has been recorded in our settings since 2015, with 31 cases having been documented during the period 2014-2017. The molecular investigation of strains from the above period showed the emergence of a methicillin-susceptible, mupirocin- and fusidic acid-resistant Staphyloccocus aureus clone that belongs to the ST121 complex and carries both epidermolysin (eta/etb) genes. We concluded that the SSSS caused by the newly emerged, highly virulent community-associated-methicillin sensitive S. aureus strains that have been encountered lately is more severe than impetigo. Physicians should be aware of the probability of SSSS epidemics from strains that are resistant to mupirocin and fusidic acid, which have been used irrationally and excessively.

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Source
http://dx.doi.org/10.1099/jmm.0.000871DOI Listing
January 2019
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