Implementing Universal Varicella Vaccination in Europe: The Path Forward.

Authors:
Vana Spoulou
Vana Spoulou
Aghia Sophia Children's Hospital
Sophie Alain
Sophie Alain
Univ. Limoges
Limoges | France
Giovanni Gabutti
Giovanni Gabutti
University of Salento
Italy
Carlo Giaquinto
Carlo Giaquinto
University of Padova
Italy
Johannes Liese
Johannes Liese
University of W├╝rzburg
Germany
Timo Vesikari
Timo Vesikari
University of Tampere Medical School
Finland

Pediatr Infect Dis J 2019 Feb;38(2):181-188

University of Tampere Medical School, Tampere, Finland.

Varicella is a common vaccine-preventable disease that usually presents as a mild disorder but can lead to severe complications. Before the implementation of universal varicella vaccination (UVV) in some European countries, the burden of varicella disease was broadly similar across the region. Despite this, countries adopted heterogeneous varicella vaccination strategies. UVV is currently recommended in 12 European countries. Known barriers to UVV implementation in Europe include (1) a perceived low disease burden and low public health priority; (2) cost-effectiveness and funding availability; (3) concerns related to a shift in varicella disease and incidence of herpes zoster and (4) safety concerns related to measles, mumps, rubella and varicella-associated febrile seizures after the first dose. Countries that implemented UVV experienced decreases in varicella incidence, hospitalizations and complications, showing overall beneficial impact. Alternative strategies targeting susceptible individuals at higher risk of complications have been less effective. This article discusses ways to overcome the barriers to move varicella forward as a truly vaccine preventable disease.

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Source
http://dx.doi.org/10.1097/INF.0000000000002233DOI Listing
February 2019
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