Pigmented Conjunctival Lesions as Presenting Signs of Vaginal Melanoma.

Authors:
Dr. Paul O Phelps, MD
Dr. Paul O Phelps, MD
NorthShore University HealthSystem
Attending Surgeon
Ophthalmology, Ophthalmic Plastic and Reconstructive Surgery, Ophthalmic Pathology
Chicago, IL | United States
Martha J Farber
Martha J Farber
Albany Stratton Veterans Affairs Medical Center
Dale R Meyer
Dale R Meyer
Lions Eye Institute
United States

Ocul Oncol Pathol 2018 Sep 23;4(2):79-81. Epub 2017 Aug 23.

Ophthalmic Plastic Surgery, Lions Eye Institute-Albany Medical Center, Slingerlands, NY, USA.

A 43-year-old woman was referred to an oculoplastic surgeon for the evaluation of 2 small pigmented lesions in the tarsal conjunctiva. She underwent a biopsy of the lesions, both of which were found to be consistent with metastatic melanoma. Follow-up with the patient revealed that she had been hospitalized for balance issues and headaches. An MRI of her brain revealed a hemorrhagic mass and several smaller foci suspicious for metastatic lesions. A thorough workup included an evaluation for bloody vaginal discharge. Biopsy of a pigmented portion of the vaginal mucosa lesion revealed BRAF-positive melanoma. This was determined to be the primary site of her malignant metastatic melanoma, which caused her death within 6 months of presentation.

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Source
http://dx.doi.org/10.1159/000478278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167657PMC
September 2018
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