Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier-Hunziker syndrome.

Authors:
Ning Duan
Ning Duan
Institute and Hospital of Stomatology
China
Wen-mei Wang
Wen-mei Wang
Nanjing Stomatological Hospital
China
Xiang Wang
Xiang Wang
Queen's University
Kingston | Canada

World J Clin Cases 2018 Sep;6(10):322-334

Department of Oral Medicine, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, Jiangsu Province, China.

Labial and oral melanotic macules are commonly encountered in a broad range of conditions ranging from physiologic pigmentation to a sign of an underlying life-threatening disease. Although Laugier-Hunziker syndrome (LHS) shares some features of labial and oral pigmentation with a variety of conditions, it is a benign and acquired condition, frequently associated with longitudinal melanonychia. Herein, the demographic, clinical, dermoscopic, and pathological aspects of LHS were reviewed comprehensively. The important differential diagnoses of mucocutaneous and nail pigmentation are provided. An accurate diagnosis is crucial to design a reasonable medical strategy, including management options, malignant transformation surveillance, and psychological support. It is important that clinicians conduct long-term follow-up and surveillance due to the potential risks of malignant transformation and local severe complications in some conditions.

Download full-text PDF

Source
http://dx.doi.org/10.12998/wjcc.v6.i10.322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163135PMC
September 2018
5 Reads

Publication Analysis

Top Keywords

labial oral
12
dermoscopic pathological
8
melanotic macules
8
malignant transformation
8
oral melanotic
8
clinical dermoscopic
8
laugier-hunziker syndrome
8
pathological aspects
8
clinicians conduct
4
condition frequently
4
support clinicians
4
demographic clinical
4
aspects lhs
4
melanonychia demographic
4
longitudinal melanonychia
4
associated longitudinal
4
frequently associated
4
benign acquired
4
follow-up surveillance
4
oral pigmentation
4

References

(Supplied by CrossRef)

Similar Publications