Distinct Laminar Processing of Local and Global Context in Primate Primary Visual Cortex.

Authors:
Maryam Bijanzadeh
Maryam Bijanzadeh
University of Utah
United States
Lauri Nurminen
Lauri Nurminen
Low Temperature Laboratory
Cincinnati | United States
Sam Merlin
Sam Merlin
University of Utah
Andrew M Clark
Andrew M Clark
National Institute of Mental Health
United States
Alessandra Angelucci
Alessandra Angelucci
University of Utah
United States

Neuron 2018 Oct 13;100(1):259-274.e4. Epub 2018 Sep 13.

Department of Ophthalmology and Visual Science, Moran Eye Institute, University of Utah, Salt Lake City, UT 84132, USA. Electronic address:

Visual perception is affected by spatial context. In visual cortex, neuronal responses to stimuli inside the receptive field (RF) are suppressed by stimuli in the RF surround. To understand the circuits and cortical layers processing spatial context, we simultaneously recorded across all layers of macaque primary visual cortex while presenting stimuli at increasing distances from the recorded cells' RF. We find that near versus far-surround stimuli activate distinct layers, thus revealing unique laminar contributions to the processing of local and global spatial context. Stimuli in the near-surround evoke the earliest subthreshold responses in superficial and upper-deep layers, and earliest suppression of spiking responses in superficial layers. Conversely, far-surround stimuli evoke the earliest subthreshold responses in feedback-recipient layer 1 and lower-deep layers, and earliest suppression of spiking responses almost simultaneously in all layers, except 4C, where suppression emerges last. Our results suggest distinct circuits for local and global signal integration.

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Distinct V1 Layers Process Local and Global Visual Context


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http://dx.doi.org/10.1016/j.neuron.2018.08.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279245PMC
October 2018
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