Drug Target Commons 2.0: a community platform for systematic analysis of drug-target interaction profiles.

Database (Oxford) 2018 01 1;2018:1-13. Epub 2018 Jan 1.

Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.

Drug Target Commons (DTC) is a web platform (database with user interface) for community-driven bioactivity data integration and standardization for comprehensive mapping, reuse and analysis of compound-target interaction profiles. End users can search, upload, edit, annotate and export expert-curated bioactivity data for further analysis, using an application programmable interface, database dump or tab-delimited text download options. To guide chemical biology and drug-repurposing applications, DTC version 2.0 includes updated clinical development information for the compounds and target gene-disease associations, as well as cancer-type indications for mutant protein targets, which are critical for precision oncology developments.

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http://dx.doi.org/10.1093/database/bay083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146131PMC

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January 2018

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