Epidemiological aspects of travel-related systemic endemic mycoses: a GeoSentinel analysis, 1997-2017.

Authors:
Rhett J Stoney
Rhett J Stoney
Harvard Medical School
Kristina M Angelo
Kristina M Angelo
Centers for Disease Control and Prevention
Thierry Rolling
Thierry Rolling
Centro Nacional de Biotecnología
Spain
Martin P Grobusch
Martin P Grobusch
Center of Tropical Medicine and Travel Medicine
New York | United States
Michael Libman
Michael Libman
McGill University
Canada
Rogelio Lopez-Velez
Rogelio Lopez-Velez
Ramón y Cajal Hospital
Spain
Alexandre Duvignaud
Alexandre Duvignaud
Centre Hospitalier Universitaire de Bordeaux

J Travel Med 2018 08;25(1)

Department of Global Health, Boston University School of Public Health, Boston, MA, USA.

Background: International travel has increased in the past few decades, placing more travellers at risk of acquiring systemic endemic mycoses. There are limited published data on systemic endemic mycoses among international travellers. We report epidemiological characteristics of non-migrant, international travellers who acquired systemic endemic mycoses during travel.

Methods: We analysed records of non-migrant international travellers with a confirmed diagnosis of histoplasmosis, coccidioidomycosis, paracoccidioidomycosis, blastomycosis or talaromycosis reported from 1997 through 2017 to GeoSentinel, a global surveillance network now consisting of 70 travel or tropical medicine centres in 31 countries.

Results: Sixty-nine records met the inclusion criteria. Histoplasmosis was most frequently reported; the 51 travellers with histoplasmosis had the lowest median age (30 years; range: 8-85) and shortest median duration of travel (12 days; range: 5-154). Coccidioidomycosis was reported in 14 travellers; travellers with coccidioidomycosis were older (median 62 years; range: 22-78) and had the longest median number of days between return from travel and presentation to a GeoSentinel site (55 days; range: 17-273). Almost all travellers with coccidioidomycosis were exposed in the USA. Other systemic endemic mycoses were less frequently reported, including blastomycosis (three travellers) and talaromycosis (one traveller).

Conclusions: Although relatively rare, systemic endemic mycoses should be considered as potential travel-related infections in non-migrant international travellers. Epidemiological exposures should be used to guide diagnostic evaluations and treatment.

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https://academic.oup.com/jtm/article/doi/10.1093/jtm/tay055/
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http://dx.doi.org/10.1093/jtm/tay055DOI Listing
August 2018
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