Cutaneous Nontuberculous Mycobacterial Infections in Alberta, Canada: An Epidemiologic Study and Review.

Authors:
Megan A Sander
Megan A Sander
University of Calgary
Gregory J Tyrrell
Gregory J Tyrrell
University of Alberta
Canada

J Cutan Med Surg 2018 Sep/Oct;22(5):479-483. Epub 2018 May 17.

3 Division of Diagnostic and Applied Microbiology, Department of Laboratory Medicine and Pathology, University of Alberta and the Alberta Provincial Public Health Laboratory, WC Mackenzie Health Sciences Centre, Edmonton, AB, Canada.

Background: Cutaneous infections caused by nontuberculous mycobacteria (NTM) occur infrequently. Nonetheless, the incidence of NTM infections is reported to be increasing. In Canada, cutaneous NTM infections have not been well described.

Objectives: A database review from 2006 to 2016 was done to assess species frequency, incidence, and trends of the most common cutaneous NTMs in the province of Alberta, Canada. We also reviewed major diagnostic and epidemiologic aspects of NTM cutaneous infections with a focus on Mycobacterium marinum.

Results: A database search identified 244 cases of NTM infections. Mycobacterium avium-intracellulare complex had the highest incidence, causing 64% of cases. Rapid growers ( Mycobacterium abscessus, Mycobacterium chelonae, Mycobacterium fortuitum) caused 23% and M marinum 13%. Information on infection site was available for 117 cases. There was no difference noted in sex distribution; however, differences in age groups between species were noted.

Conclusions: The incidence of NTM cutaneous infections in Alberta, Canada, was reported for the first time and the incidence of M marinum was found to be similar to that reported in the worldwide literature. Patients' age groups were different between species. Knowledge of the unique microbiological features of NTMs and the role of the diagnostic laboratory are important.

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http://dx.doi.org/10.1177/1203475418776945DOI Listing
December 2018
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References

(Supplied by CrossRef)

Ramos-e-Silva M et al.
2013

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