Deep head and neck infections: outcome following empirical therapy with early generation antibiotics.

Authors:
Lalee Varghese
Lalee Varghese
Christian Medical College
India
Suma Susan Mathews
Suma Susan Mathews
Christian Medical College
Vellore | India
V Rupa
V Rupa
Christian Medical College
India

Trop Doct 2018 Jul 14;48(3):179-182. Epub 2018 May 14.

4 Professor, Department of Otorhinolaryngology, Christian Medical College, Vellore.

In order to study the bacteriological profile, antibiotic sensitivity and outcome following empirical therapy with early generation antibiotics in patients with deep head and neck infection, a retrospective review of 42 patients admitted for drainage and intravenous antibiotic therapy was performed. Ludwig's angina was the commonest infection, with the most common organisms isolated being Group F ß-haemolytic (15%) and non-haemolytic (12.5%) streptococcus. All streptococci and anaerobic gram-positive cocci were susceptible to penicillin. S. aureus isolates were oxacillin-sensitive and enterococcus isolates were ampicillin-sensitive. All 42 patients received empirical therapy with either intravenous penicillin or its derivatives. In only three patients was a change of antibiotic required based on culture and sensitivity results. Early generation antibiotics appear ideal as empirical therapy for deep head and neck infection.

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http://dx.doi.org/10.1177/0049475518774472DOI Listing
July 2018
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References

(Supplied by CrossRef)
Article in Radiol North Am
Gonzalez-Beicos A et al.
Radiol North Am 2012
Article in Radiol Clin North Am
Rana RS et al.
Radiol Clin North Am 2011
Article in Am J Otolaryngol
Bakir S et al.
Am J Otolaryngol 2012
Article in Head Neck
Huang TT et al.
Head Neck 2004
Article in Acta Otolaryngol
Kinzer S et al.
Acta Otolaryngol 2009
Article in J Oral Maxillofac Surg
Rega AJ et al.
J Oral Maxillofac Surg 2006
Article in J Oral Maxillofac Surg
Brook I et al.
J Oral Maxillofac Surg 2004
Article in Acta Otorhinolaryngol Ital
Songu M et al.
Acta Otorhinolaryngol Ital 2011
Article in Infect Drug Resist
Yang SW et al.
Infect Drug Resist 2008
Article in Singapore Med J
Lee YQ et al.
Singapore Med J 2011

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