Pediatr Allergy Immunol 2018 Apr 21. Epub 2018 Apr 21.
Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.
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Clin Exp Allergy 2017 May 2;47(5):684-692. Epub 2017 Mar 2.
Novartis Pharma GmbH, Nürnberg, Germany.
Background: Most data on chronic spontaneous urticaria (CSU) originate from highly selected patient populations treated at specialized centres. Little is known about CSU patient characteristics and the burden of CSU in routine clinical practice. AWARE (A World-wide Antihistamine-Refractory chronic urticaria patient Evaluation) is an ongoing global study designed to assess chronic urticaria in the real-life setting. Read More
Clin Transl Allergy 2015 17;5:29. Epub 2015 Aug 17.
Novartis Pharma AG, Basel, Switzerland.
Background: Chronic spontaneous urticaria (CSU) formerly known as chronic idiopathic urticaria (CIU) is a severe and distressing skin condition that remains uncontrolled in approximately one half of patients, despite the use of licensed, recommended doses of modern, second-generation H1-antihistamines. So far, the humanistic, societal and economic burden of CSU/CIU has not been well quantified. Therefore it is important to broaden our understanding of how CSU/CIU impacts patients, society, and healthcare systems, by determining the disease burden of CSU/CIU and the associated unmet need; as well as to further guide the use of new treatments in an efficient and cost-effective manner. Read More
Dermatol Ther (Heidelb) 2018 Mar 10;8(1):69-83. Epub 2018 Feb 10.
Herbert Wertheim School of Medicine, Florida International University, Miami, FL, USA.
Introduction: Few studies have described chronic idiopathic/spontaneous urticaria (CIU/CSU) healthcare burden in adults, while this information remains largely unknown in children. We aimed to describe treatment patterns, healthcare resource utilization (HRU), and costs in CIU/CSU pediatric patients, as well as to compare HRU and costs in CIU/CSU and CIU/CSU-free pediatric patients.
Methods: Medicaid claims from four states (09/01/2013-03/31/2016) were used to identify patients less than 12 years old. Read More
Allergy Asthma Proc 2018 May 7;39(3):201-211. Epub 2018 Mar 7.
Herbert Wertheim School of Medicine, Florida International University, Miami, Florida.
Background: Chronic idiopathic urticaria (CIU)/spontaneous urticaria (CSU) is defined by the presence of wheals, angioedema, or both for ≥6 weeks, with or without an identifiable trigger. Real-world health care data among children with CIU/CSU remain scarce.
Objectives: To describe treatment patterns, health care resource utilization (HRU), and costs in pediatric patients with CIU/CSU (<12 years old) and to compare these with pediatric patients without CIU/CSU. Read More