The Prevalence of Healthcare-Associated Infections in Mainland China: A Systematic Review and Meta-analysis.

Infect Control Hosp Epidemiol 2018 06 15;39(6):701-709. Epub 2018 Apr 15.

1Infection Control Program and WHO Collaborating Centre on Patient Safety,University of Geneva Hospitals and Faculty of Medicine,Geneva,Switzerland.

OBJECTIVETo assess the prevalence of healthcare-associated infections (HAIs) in mainland China.DESIGNSystematic review and meta-analysis.SETTINGAdults and children from secondary and tertiary acute-care hospitals in mainland China.METHODSWe searched PubMed, the China National Knowledge Infrastructure, and Wan Fang for multicenter point-prevalence surveys of acute-care hospitals in mainland China from January 2006 to August 2016. All reports related to HAI, using a point-prevalence methodology and published either in English or Chinese were eligible.RESULTSIn total, 3,021 publications were identified; 115 were eligible for quality assessment and data abstraction. The weighted HAI prevalence (95% confidence interval [CI]) overall, in general hospitals, children's hospitals, maternal and child health hospitals, and oncology hospitals were 3.12% (95% CI, 2.94%-3.29%), 3.02% (95% CI, 2.79%-3.26%), 4.43% (95% CI, 3.39%-5.47%), 1.88% (95% CI, 1.47%-2.29%), and 3.96% (95% CI, 3.12%-4.79%), respectively. In general hospitals, prevalence was highest in adult intensive care units (26.07%; 95% CI, 23.03%-29.12%), followed by surgery (3.26%; 95% CI, 2.96%-3.57%), and internal medicine (3.06%; 95% CI, 2.67%-3.46%). Overall, lower respiratory tract infection was the most frequent HAI (24,185, 47.28%), followed by urinary tract infection (5,773, 11.29%) and upper respiratory tract infection (5,194, 10.15%). Gram-negative bacilli were the most frequently isolated pathogens, and Pseudomonas aeruginosa (3,395, 14.91%), and Escherichia coli (2,918, 12.82%) were the most common single microorganisms.CONCLUSIONSThis study is the largest systematic review on the prevalence of HAI in mainland China. These results provide a benchmark for future PPSs and a reference for infection prevention and control strategies in mainland China.Infect Control Hosp Epidemiol 2018;39:701-709.

Download full-text PDF

Source
http://dx.doi.org/10.1017/ice.2018.60DOI Listing
June 2018
10 Reads

Publication Analysis

Top Keywords

mainland china
12
tract infection
12
95%
9
acute-care hospitals
8
systematic review
8
respiratory tract
8
hospitals mainland
8
general hospitals
8
prevalence healthcare-associated
8
healthcare-associated infections
8
hospitals
7
mainland
6
prevalence
5
intensive care
4
care units
4
units 2607%
4
prevalence highest
4
2607% 95%
4
hospitals prevalence
4
highest adult
4

References

(Supplied by CrossRef)
Deadly sins of antibiotic abuse in China
Wang et al.
Infect Control Hosp Epidemiol 2017
The distribution and antibiotic resistance of clinical isolates from blood culture in 2012 CHINET surveillance program in China
Li et al.
Chin J Infect Chemother 2014

Similar Publications