Med J Aust 2018 Apr;208(7):308
University of Sydney, Sydney, NSW.
Clin Exp Allergy 2016 Aug 31;46(8):1099-110. Epub 2016 May 31.
Children's Hospital Westmead, Sydney, NSW, Australia.
Background: Recent epidemiological studies indicate increases in Australian, UK and US hospital anaphylaxis admission rates.
Objectives: The aim of this study was to determine whether Australian anaphylaxis fatalities are increasing in parallel and to examine the characteristics of fatalities recorded in the National Coronial Information System (NCIS).
Methods: Time trends in Australian anaphylaxis fatalities were examined using data derived from the Australian Bureau of Statistics (ABS) 1997-2013 and the NCIS 2000-2013, the latter providing additional information to verify cause and identify risk factors. Read More
J Allergy Clin Immunol 2007 Oct;120(4):878-84
Australian Centre for Asthma Monitoring, Camperdown, NSW, Australia.
Background: Recent investigations in developed countries have found marked increases in the prevalence of allergic conditions.
Objective: We sought to examine recent time trends in the prevalence of anaphylaxis, angioedema, and urticaria by describing trends and age and sex differentials in hospitalizations for these conditions in Australia.
Methods: Data on hospital admissions and deaths for anaphylaxis, angioedema, and urticaria were extracted for the periods 1993-1994 to 2004-2005 and 1997-2004, respectively. Read More
Ann Allergy Asthma Immunol 2009 Dec;103(6):502-7
Montgomery Family Practice Residency Program, Montgomery Hospital Medical Center, Norristown, Pennsylvania, USA.
Background: Angiotensin-converting enzyme inhibitors (ACE-Is) are associated with angioedema, a potentially life-threatening adverse reaction. Although multiple studies have been conducted in tertiary care emergency departments (EDs), scarce data are available about the presentation and management of ACE-I-induced angioedema (AIIA) in the community hospital ED.
Objective: To describe the frequency, presentation, and management of AIIA in patients seen in a community hospital ED. Read More
Medicine (Baltimore) 2015 Nov;94(45):e1939
Service des Urgences, Centre de Référence associé sur les angiœdèmes à kinines (CRéAk), Assistance Publique-Hôpitaux de Paris, Hôpital Louis Mourier, Université Paris 7, 92 700 Colombes (NJ, JA); Urgences et (P-GR, FL, LH, FA); SAMU-SMUR 93, Assistance Publique - Hôpitaux de Paris, Hôpital Avicenne, Université Paris 13, 93 000 Bobigny (P-GR, FL, FA); Urgences, Assistance Publique - Hôpitaux de Paris, Hôpital Jean Verdier, Université Paris 13, 93 140 Bondy (AL, AK); Urgences, Hôpital d'Eaubonne, 95 600 Eaubonne (AL); Urgences, Hôpital de Gonesse, 95 500 Gonesse (MY); Service de Médecine Interne, DHUi2B, Centre de Référence associé sur les angiœdèmes à kinines (CRéAk), Assistance Publique - Hôpitaux de Paris, Hôpital Saint-Antoine, Université Paris 6, 75 012 Paris, France (OF).
The number of cases of acquired angioedema related to angiotensin converting enzyme inhibitors induced (ACEI-AAE) is on the increase, with a potential concomitant increase in life-threatening attacks of laryngeal edema. Our objective was to determine the main characteristics of ACEI-AAE attacks and, in doing so, the factors associated with likelihood of hospital admission from the emergency department (ED) after a visit for an attack.A prospective, multicenter, observational study (April 2012-December 2014) was conducted in EDs of 4 French hospitals in collaboration with emergency services (SAMU 93) and a reference center for bradykinin-mediated angioedema. Read More