Clin Exp Rheumatol 2018 Feb 7. Epub 2018 Feb 7.
Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, Brazil.
Dig Dis Sci 2011 Mar 15;56(3):812-8. Epub 2010 Jul 15.
Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, 134 Shinchon-Dong Seodaemun-ku, Seoul, 120-752, Korea.
Background: Intestinal Behçet's disease (BD) is a chronic inflammatory bowel disease, as are Crohn's disease (CD) and ulcerative colitis (UC). But unlike CD and UC, serologic markers for intestinal BD are not well known. Recently, anti-α-enolase antibody (AAEA) has been detected in sera from BD patients. Read More
Clin Exp Rheumatol 2007 Jul-Aug;25(4 Suppl 45):S70-5
Division of Rheumatology, Gulhane Military School of Medicine, Ankara, Turkey.
Objectives: Basic and clinical studies have revealed a strong correlation between matrix metalloproteinases (MMPs), particularly MMP-2 and MMP-9, and the formation of abdominal aortic aneurysms. In addition, previous studies have clearly shown that MMP-2 and MMP-9 play an important role in the pathogenesis of vasculitis characterized by aneurysm formation such as Kawasaki disease, temporal arteritis and Takayasu arteritis. Depending on those findings, we hypothesized that circulating MMP-2 and MMP-9 could be useful markers to demonstrate vascular aneurysmatic involvement in patients with Behçet's disease (BD). Read More
Clin Rheumatol 2007 Aug 20;26(8):1263-7. Epub 2006 Dec 20.
Rheumatology Division, Faculty of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, 3o andar, sala 3133, Pacaembu, São Paulo-SP, CEP 01246-903, Brazil.
The Behçet's Disease Current Activity Form (BDCAF) is a clinical instrument used to assess the activity of Behçet's disease (BD), which was originally developed in English. The aim of the present study was to perform a cross-cultural adaptation of the BDCAF to Brazilian Portuguese language and to evaluate its reliability in a population of Brazilian patients with BD. Brazilian Portuguese version of the BDCAF, named BR-BDCAF, was obtained according to established guidelines. Read More
Arthritis Rheum 2003 Jul;48(7):2025-35
Cutaneous Biology Research Institute, and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea.
Objective: To identify and recombine a protein of the human dermal microvascular endothelial cell (HDMEC) that specifically reacts with anti-endothelial cell antibody (AECA) in the serum of patients with Behçet's disease (BD), and to evaluate the usefulness of this protein in BD.
Methods: The proteomics technique, with 2-dimensional gel electrophoresis and matrix-assisted laser desorption ionization-time-of-flight (MALDI-TOF) mass spectrometry, was used to identify and recombine HDMEC antigen. Western blotting and enzyme-linked immunosorbent assay (ELISA) of recombinant protein isolated by gene cloning were performed on serum from healthy controls, patients with BD, and patients with other rheumatic diseases (rheumatoid arthritis, systemic lupus erythematosus, and Wegener's granulomatosis). Read More