Effects of Chronic Musculoskeletal Pain on Fertility Potential in Lean and Overweight Male Patients.

Authors:
Dr. Hiva Alipour, DVM, PhD
Dr. Hiva Alipour, DVM, PhD
Aalborg University
Postdoc
Reproductive Medicine
Aalborg | Denmark

Pain Res Manag 2017 24;2017:4628627. Epub 2017 Dec 24.

Department of Health Science and Technology, Biomedicine Group, The Faculty of Medicine, Aalborg University, Aalborg, Denmark.

Both chronic pain and obesity are known to affect reproductive hormone profiles in male patients. However, the effect of these conditions, alone or in combination, on male fertility potential has received less attention. 20 chronic musculoskeletal pain patients and 20 healthy controls were divided into lean and overweight subgroups according to their BMI. Current level of chronic pain (visual analogue scale) and pressure pain thresholds (PPTs) in 16 predefined sites, classically described and tested as painful points on the lower body, were measured. Levels of reproductive hormone and lipid profiles were assessed by ELISA. Sperm concentration and motility parameters were analyzed using a computer-aided sperm analysis system. Sperm concentration, progressive motility, and percentage of hyperactivated sperm were generally lower in the chronic pain patients in both lean and overweight groups. The overweight control and the lean chronic pain groups demonstrated a significantly lower percentage of progressively motile sperm compared with the lean control group, suggesting that musculoskeletal chronic pain may have a negative influence on sperm quality in lean patients. However, due to the potential great negative influence of obesity on the sperm parameters, it is difficult to propose if musculoskeletal chronic pain also influenced sperm quality in overweight patients. Further research in chronic pain patients is required to test this hypothesis.

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Source
http://dx.doi.org/10.1155/2017/4628627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757111PMC
September 2018
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References

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2004
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British Journal of General Practice 1997

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