JAAD Case Rep 2017 Nov 6;3(6):515-518. Epub 2017 Nov 6.
Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas.
Download full-text PDF
Pol Merkur Lekarski 2004 May;16(95):493-4
Klinika Chirurgii Onkologicznej Centrum Onkologii, Instytut im. Marii Skłodowskiej-Curie, Oddział w Krakowie.
Angiosarcoma arising in the area of chronically lymphoedematous extremity is referred to as Stewart-Treves syndrome. In the world literature we can find about 400 cases of Stewart-Treves syndrome occurring after treatment for breast cancer. There are also occasional case reports of Stewart-Treves syndrome within chronically lymphoedematous upper extremity not related to breast cancer treatment and within chronically lymphoedematous leg. Read More
Pathology 2016 Dec 22;48(7):697-704. Epub 2016 Oct 22.
Department of Pathology, University of Michigan Health System, Ann Arbor, MI, United States. Electronic address:
Angiosarcoma (AS) is an uncommon vascular malignancy with an aggressive clinical course. Radiation-associated angiosarcoma (RAAS) and Stewart-Treves syndrome are associated with MYC gene amplification and protein overexpression, while other radiation-associated vascular lesions including atypical vascular lesions (AVL) are not associated with MYC overexpression. In contrast, de novo AS represent a group of molecularly heterogeneous tumours, for which MYC expression has not been extensively examined. Read More
Pan Afr Med J 2014 1;19. Epub 2014 Sep 1.
Department of Surgical Oncology, National Institute of Oncology, Rabat, Morocco.
The Stewart-Treves syndrome was first described in 1948, it's an angiosarcoma developed on a longstanding lymphadenomatous limb, more often after radical mastectomy. Diagnosis is made on skin biopsy and the prognosis is poor when radical surgery can't be performed. We report the case on a Stewart-Treves syndrome in a sixty-six years old woman who underwent radical mastectomy for breast carcinoma ten years earlier. Read More
Radiol Case Rep 2012 7;7(4):693. Epub 2015 Dec 7.
Stewart-Treves syndrome is a rare cutaneous angiosarcoma with a poor prognosis. Physicians must be aware of this lethal syndrome, especially in patients who have been treated for breast cancer with radiation and lymph-node dissection (such as the case reported here). Patients who develop unexplained enlarging plaques of coalescing purple papules should have immediate biopsy for early diagnosis of Stewart-Treves syndrome. Read More