Acta Crystallogr E Crystallogr Commun 2017 Oct 19;73(Pt 10):1497-1500. Epub 2017 Sep 19.
S.Yunusov Institute of the Chemistry of Plant Substances Academy of Sciences of, Uzbekistan Mirzo Ulugbek Str., 77, Tashkent 100170, Uzbekistan.
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Arq Gastroenterol 2018 Jan-Mar;55(1):28-32
The Liver Clinic´s Research Group from Gastroenterology and Hepatology Department, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico.
Background: Acid suppression has been associated with adverse events; such as, enteric infections. Proton pump inhibitors (PPI) are frequently prescribed in patients with cirrhosis, but is unclear if PPI are associated with the development of bacterial infections in these patients.
Objective: To assess the impact of PPI intake on the development of bacterial, viral and fungal infections in patients with cirrhosis. Read More
Pak J Biol Sci 2017 ;20(4):179-188
Department of Biology, Mu'tah University, Al-Karak, Jordan.
Background And Objective: The patients with Diabetes Mellitus (DM) have malfunction in bladder which prompt urine accumulation in its pool which serves a decent situation to the microbes to be develop and cause Urinary Tract Infection (UTI). The UTI is the most infectious disease that affects both males and females. This study was designed to detect the bacterial species responsible for UTI in both diabetic and non-diabetic patients in Ma'an province, Jordan. Read More
Tunis Med 2017 Novembre;95(11):1002-1070
Proc Natl Acad Sci U S A 2016 08 18;113(31):8813-8. Epub 2016 Jul 18.
CNRS UMR5240, Microbiologie Adaptation et Pathogénie, 69622 Villeurbanne, France; Université Claude Bernard Lyon 1, 69100 Villeurbanne, France; International Center for Infectiology Research (CIRI), International Center for Infectiology Research, Université de Lyon, 69364 Lyon, France; INSERM U1111, 69364 Lyon, France; Ecole Normale Supérieure de Lyon, 69364 Lyon, France; Université Claude Bernard Lyon 1, Centre International de Recherche en Infectiologie, 69364 Lyon, France; CNRS UMR5308, 69007 Lyon, France;
A highly conserved DNA uptake system allows many bacteria to actively import and integrate exogenous DNA. This process, called natural transformation, represents a major mechanism of horizontal gene transfer (HGT) involved in the acquisition of virulence and antibiotic resistance determinants. Despite evidence of HGT and the high level of conservation of the genes coding the DNA uptake system, most bacterial species appear non-transformable under laboratory conditions. Read More
PLoS One 2014 12;9(5):e97220. Epub 2014 May 12.
Thunder Bay Regional Research Institute, Ontario, Canada; Department of Physics, Lakehead University, Thunder Bay, Ontario, Canada.
In this study we developed, characterized and validated in vitro a functional superparagmagnetic iron-oxide based magnetic resonance contrast agent by conjugating a commercially available iron oxide nanoparticle, Molday ION Rhodamine-B Carboxyl (MIRB), with a deimmunized mouse monoclonal antibody (muJ591) targeting prostate-specific membrane antigen (PSMA). This functional contrast agent is intended for the specific and non-invasive detection of prostate cancer cells that are PSMA positive, a marker implicated in prostate tumor progression and metastasis. The two-step carbodiimide reaction used to conjugate the antibody to the nanoparticle was efficient and we obtained an elemental iron content of 1958 ± 611 per antibody. Read More