Cleve Clin J Med 2017 Dec;84(12):918
Department of Internal Medicine, University of California Davis, Sacramento, CA, USA.
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Ann Dermatol Venereol 2008 Apr 25;135(4):287-90. Epub 2008 Mar 25.
Service de dermatologie, hôpital Fournier, CHU de Nancy, 36, quai de la Bataille, 54000 Nancy, France.
Background: Leser-Trélat sign involves the combined sudden onset of seborrheic keratosis and cancer. However, some doubt surrounds the existence of this syndrome. We report a case of Leser-Trélat sign that led to the discovery of Sézary syndrome. Read More
Case Rep Oncol 2011 Mar 29;4(1):175-7. Epub 2011 Mar 29.
Department of Dermatology, Centre Hospitalier de Saint-Brieuc, Saint-Brieuc, France.
Leser-Trélat sign is characterized by the abrupt appearance of multiple seborrheic keratoses in association with underlying malignant disease. A case of Leser-Trélat sign in a 66-year-old healthy woman is presented. Evaluation and follow-up for the development of malignancy over a 2-year period failed to reveal any evidence of malignancy. Read More
J Hematol Oncol 2010 Jan 11;3. Epub 2010 Jan 11.
Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy.
Leser-Trélat syndrome is characterized by the eruptive appearance of multiple seborrheic keratoses in association with underlying malignant disease. Usually, the sign of Leser-Trélat is associated with adenocarcinoma, most frequently of the colon, breast, or stomach, but also of the lung, kidney, liver, and pancreas. Herein, we present a case that we believe is the first report of the sign of Leser-Trélat in association with occult gastric adenocarcinoma and the anamnestic oncologic history of five other multiple primitive cancers. Read More