J Neurovirol 2018 Feb 14;24(1):128-131. Epub 2017 Dec 14.
Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.
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Eur J Paediatr Neurol 2016 May 19;20(3):435-8. Epub 2016 Feb 19.
Pediatric Neurology and Neurodevelopment Unit, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address:
Background: Subacute sclerosing panencephalitis is a devastating neurodegenerative disease with a characteristic clinical course. Atypical presentations may be seen in 10% of the cases.
Aims: To describe the atypical clinical and radiological features of SSPE in a child form endemic country. Read More
BMJ Case Rep 2012 Dec 14;2012. Epub 2012 Dec 14.
Department of Neurology, CSMMU Lucknow, Lucknow, Uttar Pradesh, India.
Subacute sclerosing panencephalitis (SSPE) is a slowly progressing inflammatory and degenerative disorder of the brain caused by a mutant measles virus. The diagnosis of SSPE is based on characteristic clinical and EEG findings (periodic complexes) and demonstration of elevated antibody titres against measles in cerebrospinal fluid. SSPE can have atypical clinical features at the onset. Read More
BMJ Case Rep 2012 Dec 23;2012. Epub 2012 Dec 23.
Department of Neurology, Chhatrapati Shahuji Maharaj Medical University, Lucknow, Uttar Pradesh, India.
Subacute sclerosing panencephalitis (SSPE) is a slowly progressive inflammatory disease of the central nervous system caused by a persistent measles virus usually affecting the childhood and adolescent age group. Clinical features at onset are very subtle and non-specific. Certain atypical features can occur at onset or during the course of illness which can be misleading. Read More
Med Sci (Basel) 2017 Nov 7;5(4). Epub 2017 Nov 7.
Department of Neurological Surgery, University of California, San Diego, 200 West Arbor Drive #8893, La Jolla, CA 92103, USA.
Subacute sclerosing panencephalitis (SSPE) is a rare progressive neurological disorder of early adolescence caused by persistent infection of the measles virus, which remains prevalent worldwide despite an effective vaccine. SSPE is a devastating disease with a characteristic clinical course in subcortical white matter; however, atypical presentations of brainstem involvement may be seen in rare cases. This review summarizes reports to date on brainstem involvement in SSPE, including the clinical course of disease, neuroimaging presentations, and guidelines for treatment. Read More