Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma.

Nucl Med Mol Imaging 2017 Dec 16;51(4):360-361. Epub 2016 Aug 16.

Department of pathology, UMC Utrecht, Utrecht, Netherlands.

A patient with a history of adenoid cystic carcinoma of the nasal cavity presented himself with bone pain and an elevated PSA level. On suspicion of metastatic prostate cancer a Ga-PSMA PET-CT was performed. The PET-CT showed numerous lung and non-sclerotic bone metastasis. Biopsy of a bone metastasis was performed and pathology showed adenoid cystic carcinoma instead of prostate cancer. Immunohistochemical PSMA staining of the primary tumour showed intense PSMA expression in adenoid cystic carcinoma tumour cells. Because of the high PSMA expression of adenoid cystic carcinoma, Ga-PSMA PET-CT might be a promising imaging modality for this malignancy.

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http://dx.doi.org/10.1007/s13139-016-0445-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721081PMC
December 2017
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