Similar Publications

Specific inactivation of an antifungal bacterial siderophore by a fungal plant pathogen.

ISME J 2021 Feb 22. Epub 2021 Feb 22.

Agricultural Biotechnology Research Center, Academia Sinica, Taipei, 11529, Taiwan.

Bacteria and fungi secrete many natural products that inhibit each other's growth and development. The dynamic changes in secreted metabolites that occur during interactions between bacteria and fungi are complicated. Pyochelin is a siderophore produced by many Pseudomonas and Burkholderia species that induces systemic resistance in plants and has been identified as an antifungal agent. Read More

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February 2021

Assessing the inactivation capabilities of two commercially available platelet component pathogen inactivation systems: effectiveness at end of shelf life.

Vox Sang 2021 Feb 22. Epub 2021 Feb 22.

Microbiology Services Laboratory - Bacteriology, NHS Blood and Transplant, London, UK.

Background And Objectives: The inactivation capabilities of the two current commercially available pathogen inactivation (PI) systems for platelet components (PC), Mirasol and Intercept, were investigated by determination of the absence of viable bacteria at the end of shelf life by testing the entire contents of the PC by enrichment culture (terminal sterility).

Methods: A pool-and-split method was used, with two treated units and one untreated control per inoculum concentration. Pairs of PC bags were inoculated with a single bacterial species. Read More

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February 2021

Antibacterial Activity of Crude Extract Against and Its Application as a Natural Disinfectant.

Front Microbiol 2020 3;11:632177. Epub 2021 Feb 3.

College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.

is an opportunistic food-borne pathogen that endangers the health of neonates and infants. This study aims to elucidate the antibacterial activity and mechanism of crude extract (CBCE) against and its application as a natural disinfectant. The antibacterial activity was evaluated by the determination of the diameter of inhibition zone (DIZ), minimum inhibitory concentration (MIC), and minimum bactericide concentration (MBC). Read More

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February 2021

Hepatitis E virus: Efficacy of pasteurization of plasma-derived VWF/FVIII concentrate determined by pig bioassay.

Transfusion 2021 Feb 19. Epub 2021 Feb 19.

Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Greifswald, Germany.

Background: Hepatitis E virus (HEV) is the leading cause of acute hepatitis throughout the world. Increasing blood component transfusion-associated HEV infections highlight the need for reliable virus inactivation procedures for plasma derivatives from pooled plasma donations.

Study Design And Methods: An animal infection study was conducted to evaluate the efficiency of HEV inactivation by pasteurization during the manufacturing process of the von Willebrand Factor/Factor VIII (VWF/FVIII) concentrate Haemate P/Humate-P (CSL Behring, Marburg, Germany). Read More

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February 2021

MicroRNA expression profiles analysis of apheresis platelets treated with vitamin B and ultraviolet-B during storage.

Transfus Apher Sci 2021 Feb 8:103079. Epub 2021 Feb 8.

Institute of Hematology, Blood Center of Shandong Province, Jinan 250014, Shandong Province, China. Electronic address:

Whether platelet (PLT) microRNA (miRNA) profiles are affected by pathogen reduction technology (PRT) using vitamin B and ultraviolet-B (VB-PRT) remains unclear. Samples from VB-PRT-treated (experimental group, E_) and untreated (control group, C_) apheresis PLTs were taken on days 1, 3 and 5 of storage, designated as E_1, E_3, E_5, C_1, C_3 and C_5, respectively. The miRNA expression profiles were assessed by DNA Nano Ball (DNB) sequencing technology, and verified by quantitive real-time fluorescence quantitative PCR (qRT-PCR). Read More

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February 2021