Transfus Apher Sci 2021 Feb 8:103079. Epub 2021 Feb 8.
Institute of Hematology, Blood Center of Shandong Province, Jinan 250014, Shandong Province, China. Electronic address:
Whether platelet (PLT) microRNA (miRNA) profiles are affected by pathogen reduction technology (PRT) using vitamin B and ultraviolet-B (VB-PRT) remains unclear. Samples from VB-PRT-treated (experimental group, E_) and untreated (control group, C_) apheresis PLTs were taken on days 1, 3 and 5 of storage, designated as E_1, E_3, E_5, C_1, C_3 and C_5, respectively. The miRNA expression profiles were assessed by DNA Nano Ball (DNB) sequencing technology, and verified by quantitive real-time fluorescence quantitative PCR (qRT-PCR). Read More