Clin Exp Pharmacol Physiol 2018 Jun 8;45(6):573-580. Epub 2018 Jan 8.
Department of Urology, The First People's Hospital of Xianyang City, Xianyang, Shaanxi, China.
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Cardiovasc Drugs Ther 2013 Jun;27(3):189-98
Department of Pathophysiology, Zhongshan Medical School, Sun Yat-sen University, 74 Zhongshan Er Road, Guangzhou, Guangdong 510080, China.
Purpose: Resveratrol could induce basal autophagy through the activation of sirtuin. In this study, we investigated the effect of resveratrol on oxidative injury of human umbilical endothelial vein cells (HUVECs) induced by oxidized low-density lipoprotein (ox-LDL) and the role of autophagy in this effect.
Methods: HUVECs were exposed to 100 mg/L ox-LDL for 24 h to cause oxidative injury. Read More
Mol Cell Endocrinol 2017 Jun 24;448:1-20. Epub 2017 Feb 24.
Molecular Endocrinology Laboratory, Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247 667, Uttarakhand, India. Electronic address:
Lipotoxicity of pancreatic β-cells is the pathological manifestation of obesity-linked type II diabetes. We intended to determine the cytoprotective effect of kaempferol on pancreatic β-cells undergoing apoptosis in palmitic acid (PA)-stressed condition. The data showed that kaempferol treatment increased cell viability and anti-apoptotic activity in PA-stressed RIN-5F cells and murine pancreatic islets. Read More
Mol Cell Biochem 2017 Jan 15;425(1-2):125-138. Epub 2016 Nov 15.
Department of Oncological Surgery, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Ouhai District, Wenzhou, 325015, Zhejiang, People's Republic of China.
Vascular endothelial cells are highly sensitive to oxidative stress, and this is one of the mechanisms by which widespread endothelial dysfunction is induced in most cardiovascular diseases and disorders. However, how these cells can survive in oxidative stress environments remains unclear. Salidroside, a traditional Chinese medicine, has been shown to confer vascular protective effects. Read More
Free Radic Biol Med 2016 06 25;95:230-42. Epub 2016 Mar 25.
Anti-stress and Health Research Center, Pharmacy College, Jinan University, Guangzhou 510632, China. Electronic address:
Resveratrol gains a great interest for its strong antioxidant properties, while the molecular mechanisms underlie the beneficial effects on psychosocial stress remain controversial. In this study, we demonstrated that resveratrol protected peritoneal macrophages and RAW 264.7 cells from stress-induced decrease in the total cell count, phagocytic capability, reactive oxygen species generation, monodansylcadaverine and mitochondrial membrane potential in stressed mice. Read More