Blood Purif 2018 22;45(1-3):46-52. Epub 2017 Nov 22.
Department of Chemical Engineering, The Pennsylvania State University, University Park, PA, USA.
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Chem Biodivers 2018 Aug 21;15(8):e1800045. Epub 2018 Jul 21.
Medical Research Department, National Institute of Occupational Safety and Health, 156 - EL Hegas Street, Cairo-, 11351, Egypt.
Breast cancer constitutes the second most prevalent cancer in Egypt, the problem needs more trends in treatment and treatment development either by regimen modification or introducing new drugs, and the main objective of this study is to screen the effects of the aqueous ethanol herbal extract of Luffa cylindrica leaves on different types of breast cancer cell lines representing different molecular subtypes of the disease. The major active constituents of the extract were tentatively identified by LC/MS which revealed the presence of phenolic compound derivatives and saponin that may be responsible in part for the activity of the extract. The emphasis was laid on the main apoptotic pathways as well as the extract effect on the normal cell line. Read More
Pediatr Neurol Briefs 2017 Feb;31(2)
Pediatrics Department, Setif University Hospital; Setif-1 University, Algeria.
Investigators from four European tertiary care hospitals (in Paris, France; Milan, Udine and Perugia, Italy) performed a case-control study of children and adolescents aged 6 to 17 years diagnosed with primary headaches in the emergency department by a pediatric neurologist using the validated ICHD-3 criteria. Read More
Oxid Med Cell Longev 2016 27;2016:5720574. Epub 2016 Dec 27.
Department of Molecular and Developmental Biology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.
The Keap1-Nrf2 system is an evolutionarily conserved defense mechanism against oxidative and xenobiotic stress. Besides the exogenous stress response, Nrf2 has been found to regulate numerous cellular functions, including protein turnover and glucose metabolism; however, the evolutionary origins of these functions remain unknown. In the present study, we searched for novel target genes associated with the zebrafish Nrf2 to answer this question. Read More
Headache 2016 Jan 6;56(1):95-103. Epub 2015 Dec 6.
Iranian Center of Neurological Research, Tehran University of Medical Sciences, Tehran, Iran.
Background: Uncontrolled studies in human have suggested that memantine might be a suitable option for migraine prophylaxis.
Objective: To assess the efficacy and tolerability of memantine for migraine prophylaxis.
Methods: This was a 12-week randomized double-blind placebo-controlled parallel-group study. Read More
Science 2006 Jan;311(5759):381-4
INSERM-CEA Cognitive Neuroimaging Unit, Service Hospitalier Frédéric Joliot, Commissariat à l'Energie Atomique, 91401 Orsay Cedex, France.
Does geometry constitute a core set of intuitions present in all humans, regardless of their language or schooling? We used two nonverbal tests to probe the conceptual primitives of geometry in the Mundurukú, an isolated Amazonian indigene group. Mundurukú children and adults spontaneously made use of basic geometric concepts such as points, lines, parallelism, or right angles to detect intruders in simple pictures, and they used distance, angle, and sense relationships in geometrical maps to locate hidden objects. Our results provide evidence for geometrical intuitions in the absence of schooling, experience with graphic symbols or maps, or a rich language of geometrical terms. Read More