Lancet Infect Dis 2018 01 1;18(1):24. Epub 2017 Nov 1.
Shenzhen Key lab for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shen Zhen Research Institute, Shenzhen, China; State Key Lab of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region, China. Electronic address:
Front Microbiol 2021 2;12:682239. Epub 2021 Dec 2.
Department of Pathogen Biology, School of Basic Medicine, Public Center of Experimental Technology of Pathogen Biology Technology Platform, Southwest Medical University, Luzhou, China.
Heteroresistance can lead to treatment failure and is difficult to detect by the methods currently employed by clinical laboratories. The aim of this study was to investigate the prevalence of the amikacin-heteroresistant strains and explore potential amikacin heteroresistance mechanism through whole-genome sequencing (WGS) and quantitative reverse-transcription PCR (qRT-PCR). In this study, 13 isolates (8. Read More
Braz J Microbiol 2022 Jan 15. Epub 2022 Jan 15.
Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, Brazil.
Hemodialysis patients are at high risk for bloodstream infections associated with highest morbidity and mortality rates. Bacterial species not commonly related to such infections has been hardly identified by traditional methods. Pseudocitrobacter is a novel genus of the order Enterobacterales that is associated with carbapenemase genes and nosocomial infection. Read More
Microbiol Spectr 2022 Jan 12:e0186921. Epub 2022 Jan 12.
Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital, Zhejiang Universitygrid.13402.34 School of Medicine, Hangzhou, Zhejiang, China.
Carbapenem-resistant Pseudomonas aeruginosa (CRPA) has become a serious challenge in the clinic. Recently, the prevalence of CRPA isolates carrying the gene has been increasing in China. Ceftazidime-avibactam (CZA) has shown good efficacy against large portions of KPC-2-producing CRPA strains. Read More
mSystems 2022 Jan 11:e0116921. Epub 2022 Jan 11.
Unité EERA, Institut Pasteurgrid.428999.7, APHP, Université Paris-Saclay, Paris, France.
Carbapenemase-producing Escherichia coli (CP-) represents a major public health threat with a risk of dissemination in the community as has occurred for lineages producing extended-spectrum β-lactamases. To characterize the extent of CP- spread in France, isolates from screening and infection samples received at the French National Reference Center (F-NRC) laboratory for carbapenemase-producing were investigated. A total of 691 CP- isolates collected between 2012 and 2015 and 22 isolates collected before 2012 were fully sequenced. Read More
Environ Pollut 2022 Jan 7;297:118800. Epub 2022 Jan 7.
Department of Biomedical and Clinical Sciences, Linköping University, 58185, Linköping, Sweden.
The emergence and dissemination of carbapenem-resistant Enterobacteriaceae (CRE) constitute a major global health problem. The environment plays an important role in the dissemination of CRE, but large-scale studies on CRE in groundwater environments in animal breeding areas are scarce. The aim of this study was to investigate CRE occurrence and environmental transmission of carbapenem resistance genes in large animal breeding areas in northern China. Read More