Laryngoscope Investig Otolaryngol 2017 10 25;2(5):325-330. Epub 2017 Sep 25.
Department of Otorhinolaryngology Jena University Hospital Jena Germany.
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Clin Neurophysiol 2016 Feb 7;127(2):1675-1682. Epub 2015 Sep 7.
Integra LifeSciences Corp, Plainsboro, NJ, USA.
Objective: Peripheral nerve has the capacity to regenerate after nerve lesions; during reinnervation of muscle motor units are gradually reestablished. The aim of this study was to follow the time course of reestablishing and remodeling of motor units in relation to recovery of force after different types of nerve repair.
Methods: Reinnervation of muscle was compared clinically and electrophysiologically in complete median or ulnar nerve lesions with short gap lengths in the distal forearm repaired with a collagen nerve conduit (11 nerves) or nerve suture (10 nerves). Read More
Exp Neurol 2000 Mar;162(1):98-111
Department of Otorhinolaryngology, University of Cologne, Cologne, D-50924, Germany.
To establish the influence of prolonged denervation on the recovery of a motor nerve, the rat facial nerve was transected and denervated for 0 to 224 days. Then, the freshly transected hypoglossal nerve was sutured to the predegenerated facial nerve (hypoglossal-facial nerve anastomosis, HFA). Using this nerve cross-anastomosis paradigm we analyzed the nerve regeneration and muscle reinnervation 7 to 112 days post-suture operation (DPSO). Read More
Laryngoscope 2011 Nov;121(11):2402-5
Department of Otorhinolaryngology, University of Jena, Jena, Germany.
Objectives/hypothesis: To describe a modified facial nerve reconstruction technique for complex defects of the facial fan after parotid surgery that avoids synkinesis between upper and lower face.
Study Design: Retrospective case series.
Methods: Patients who had undergone radical parotidectomy with a large defect of the facial fan, reconstruction of the upper face by facial nerve interpositional graft, and reconstruction of the lower face by hypoglossal-facial nerve jump nerve suture were included in this series. Read More
Restor Neurol Neurosci 2011 ;29(4):227-42
Department of Anatomy, Akdeniz University, Faculty of Medicine, Antalya, Turkey.
Purpose: The outcome of severe peripheral nerve injuries requiring surgical repair (transection and suture) is usually poor. Recent work suggests that direct suture of nerves increases collagen production and provides unfavourable conditions for a proper axonal regrowth. We tested whether entubulation of the hypoglossal nerve into a Y-tube conduit connecting it with the zygomatic and buccal facial nerve branches would improve axonal pathfinding at the lesion site, quality of muscle reinnervation and recovery of vibrissal whisking. Read More