Search our Database of Scientific Publications and Authors

I’m looking for a

    Details and Download Full Text PDF:
    Ocular tuberculosis in Hospital Universiti Sains Malaysia - A case series.

    Ann Med Surg (Lond) 2017 Dec 13;24:25-30. Epub 2017 Oct 13.
    Department of Ophthalmology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
    Introduction: Ocular tuberculosis (TB) encompasses a broad spectrum of clinical manifestations affecting different structures of the eye. It is caused by, a great ancient organism that induces various types of diseases and unfavorable outcomes if unrecognized and not well treated.

    Purpose: To report the clinical profile of 34 ocular TB cases observed during 6 years period in Hospital Universiti Sains Malaysia (HUSM).

    Method: A retrospective review of medical records from 34 patients diagnosed with ocular TB in HUSM from January 2011 until December 2016.

    Results: The mean age was 43 ± 14.6 years old. Both male and female affected in about 1:1 ratio. The majority of subjects were local Malays (91.2%). Risk factors included previous contact with pulmonary TB patients (38.2%), and patients with underlying diabetes mellitus (26.5%). Most patients showed normal chest radiography (79.4%). However they had positive Mantoux test (94.1%) and raised erythrocyte sedimentation rate (ESR) value (58.8%). Uveitis was the most common ocular manifestation of ocular TB (70.6%) while the rare ocular manifestations included optic perineuritis and optic neuritis, orbital apex syndrome, orbital cellulitis, sclerokeratitis, corneal ulcer and conjunctival abscess. All patients responded well to anti-TB treatment, but visual outcome was variable.

    Conclusions: This review shows the diverse entity of ocular TB spectrum in an endemic area. Good clinical response to anti-tuberculous therapy supported the presumed diagnosis of ocular TB in majority of the cases.
    PDF Download - Full Text Link
    ( Please be advised that this article is hosted on an external website not affiliated with
    Source Status ListingPossible

    Similar Publications

    Presumed tuberculous uveitis in non-endemic country for tuberculosis: case series from a New Zealand tertiary uveitis clinic.
    Clin Exp Ophthalmol 2017 May 8;45(4):357-365. Epub 2017 Feb 8.
    Ophthalmology Department, Greenlane Clinical Centre, Auckland, New Zealand.
    Background: To describe the clinical spectrum of presumed tuberculous (TB) uveitis in a developed, non-endemic country of high immigrant population.

    Design: Retrospective review of a consecutive case series.

    Participants: All 39 patients diagnosed with presumed TB uveitis at the tertiary uveitis service in Auckland from 2007 to 2014. Read More
    Utility of QuantiFERON®-TB Gold test in diagnosis and management of suspected tubercular uveitis in India.
    Int Ophthalmol 2012 Jun 15;32(3):217-23. Epub 2012 Apr 15.
    Medical and Vision Research Foundation, Sankara Nethralaya, 18, College Road, Chennai, 600 009, India.
    The tuberculin skin test, used to detect latent systemic tuberculosis (TB), has its limitations. The utility of interferon-gamma assays, found useful in the diagnosis of latent TB, is still unestablished in tubercular uveitis. We present the results of QuantiFERON(®)-TB Gold (QFT-G) test and its relevance in the diagnosis and management of suspected tubercular uveitis in India. Read More
    Tubercular Uveitis with Ocular Manifestation as the First Presentation of Tuberculosis: A Case Series.
    J Clin Diagn Res 2016 Mar 1;10(3):NR01-3. Epub 2016 Mar 1.
    Postgraduate Department of Medicine, VIMS Bellary, Karnataka, India .
    Tuberculosis is very common disease in India. It is one of the most common causes of Granulomatous Uveitis in our Country even today. So the strongest suspicion in our mind when we are treating a case of Uveitis, should be TB. Read More
    Diagnosis and treatment of tuberculous uveitis in a low endemic setting.
    Int J Infect Dis 2013 Nov 22;17(11):e993-9. Epub 2013 May 22.
    Department of Internal Medicine and Infectious Diseases, University Medical Centre Utrecht, The Netherlands. Electronic address:
    Objective: To determine factors associated with the diagnosis of tuberculous uveitis and the response to anti-tuberculous treatment (ATT).

    Methods: A retrospective case study was performed at the University Medical Centre Utrecht between October 2007 and December 2009. Patients with possible tuberculous uveitis (TBU) were selected from all patients with an unexplained uveitis. Read More