A lignan with glucose uptake activity in 3T3-L1 adipocytes from the stem bark of Knema patentinervia.

Pak J Pharm Sci 2017 Jul;30(4):1335-1339

Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, Skudai, Johor, Malaysia.

A new naturally occurring dibenzylbutyrolactone lignan named isocubebinic ether has been isolated from Knema patentinervia. The structure was established by spectroscopic methods, which include Ultraviolet, Infrared, Nuclear Magnetic Resonance and Mass Spectrometry. The compound showed activity in the stimulation of glucose uptake by 3T3-L1 adipocytes.

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July 2017

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