Search Our Scientific Publications & Authors

Int J Mol Sci 2022 Jan 21;23(3). Epub 2022 Jan 21.

Department of Cell Biology, Physiology and Immunology, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain.

Amino acids (AA) and IGF1 have been demonstrated to play essential roles in protein synthesis and fish muscle growth. The myoblast cell culture is useful for studying muscle regulation, and omics data have contributed enormously to understanding its molecular biology. However, to our knowledge, no study has performed the large-scale sequencing of fish-cultured muscle cells stimulated with pro-growth signals. Read More

Comp Biochem Physiol A Mol Integr Physiol 2022 02 23;264:111120. Epub 2021 Nov 23.

Department of Structural and Functional Biology, Institute of Biosciences, Sao Paulo State University - UNESP, Botucatu, Sao Paulo, Brazil. Electronic address:

PiRNAs are a class of small noncoding RNAs that, in their mature form, bind to Piwi proteins to repress transposable element activity. Besides their role in gametogenesis and genome integrity, recent evidence indicates their action in non-germinative tissues. We performed a global analysis of piRNA and Piwi gene expression in the skeletal muscle of juveniles pacu (Piaractus mesopotamicus), tambaqui (Colossoma macropomum), and the hybrid tambacu to evaluate the degree of piRNA sharing among these three genotypes. Read More

Sci Rep 2021 09 29;11(1):19289. Epub 2021 Sep 29.

São Paulo State University (Unesp), Aquaculture Center of Unesp, Jaboticabal, SP, 14884-900, Brazil.

Scarce genomic resources have limited the development of breeding programs for serrasalmid fish Colossoma macropomum (tambaqui) and Piaractus mesopotamicus (pacu), the key native freshwater fish species produced in South America. The main objectives of this study were to design a dense SNP array for this fish group and to validate its performance on farmed populations from several locations in South America. Using multiple approaches based on different populations of tambaqui and pacu, a final list of 29,575 and 29,612 putative SNPs was selected, respectively, to print an Axiom AFFYMETRIX (THERMOFISHER) SerraSNP array. Read More

An Acad Bras Cienc 2021 3;93(4):e20190479. Epub 2021 Sep 3.

Universidade Federal de Mato Grosso do Sul (FAMEZ), Faculdade de Medicina Veterinária e Zootenia, Av. Sen. Filinto Müller, 2443, 79070-900 Campo Grande, MS, Brazil.

This study was carried out to determine the toxicity and biochemical and morphophysiological changes caused by Serjania erecta leaf aqueous extract in pacu (Piaractus mesopotamicus). For acute toxicity testing (CL50-4h), pacu juveniles were exposed during 4 h to Serjania erecta aqueous extract concentrations of 2.5, 12. Read More

PLoS One 2021 22;16(7):e0255006. Epub 2021 Jul 22.

Department of Structural and Functional Biology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.

Fish muscle growth is a complex process regulated by multiple pathways, resulting on the net accumulation of proteins and the activation of myogenic progenitor cells. Around 350-320 million years ago, teleost fish went through a specific whole genome duplication (WGD) that expanded the existent gene repertoire. Duplicated genes can be retained by different molecular mechanisms such as subfunctionalization, neofunctionalization or redundancy, each one with different functional implications. Read More