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J Trauma Nurs 2021 Apr-Jun 01;28(2):126-134

Mission Health, Asheville, North Carolina.

Background: Well-developed trauma programs take years of planning, dedication, and commitment to the trauma population to achieve the desired outcomes and, even more, resilience and persistence to maintain a high-quality standard of care. Despite widespread trauma care systems across the nation and their link to improved outcomes for the trauma patient, there is a paucity of literature outlining the foundational elements required to evolve and grow a successful trauma program.

Objective: The purpose of this article is to outline the key elements for developing and maintaining a successful trauma program that yields high-quality patient outcomes. Read More

Plant J 2021 Mar 5. Epub 2021 Mar 5.

Institut de biologie moléculaire des plantes-CNRS, Université de Strasbourg, Strasbourg, France.

Present-day mitochondria derive from a single endosymbiosis of an α-proteobacteria into a proto-eukaryotic cell. Since this monophyletic event, mitochondria have considerably evolved, and unique traits have been independently acquired in the different eukaryotic kingdoms. Mitochondrial genome expression and RNA metabolism have indeed highly diverged. Read More

Transfusion 2021 Mar 5. Epub 2021 Mar 5.

Duke University, Durham, North Carolina, USA.

Background: Severe blood donor adverse events are rare, but due to their rarity studying them can be difficult. To get an accurate estimate of their frequency and rate in the donor population it may be necessary to combine donation data across countries.

Study Design And Methods: International blood collection organizations (BCOs) provided data on rare/severe donor reactions as well as denominator information for their donor populations from 2015 to 2017. Read More

iScience 2021 Mar 4;24(3):102144. Epub 2021 Feb 4.

Department of Biology, Queen's University, Kingston, ON K7L 3N6, Canada.

Despite the recent availability of complete genome sequences of tumors from thousands of patients, isolating disease-causing (driver) non-coding mutations from the plethora of somatic variants remains challenging, and only a handful of validated examples exist. By integrating whole-genome sequencing, genetic data, and allele-specific gene expression from TCGA, we identified 320 somatic non-coding mutations that affect gene expression in (FDR<0.25). Read More

Heliyon 2021 Feb 16;7(2):e06281. Epub 2021 Feb 16.

Shell Petroleum Development Company of Nigeria, Port Harcourt, Nigeria.

The Niger Delta is one of the most prolific hydrocarbon provinces in the world, but information on basinal hydrogeology is scanty. Oilfield brines from nine producer wells in the Miocene reservoirs (2,472.25-3,532. Read More