Prognostic Factors of Human Immunodeficiency Virus-Infected Patients on Chronic Hemodialysis.

Blood Purif 2017 3;44(3):244-250. Epub 2017 Oct 3.

Department of Nephrology, Hospital de Santa Cruz, Lisbon, Portugal.

Background/aims: The number of human immunodeficiency virus (HIV)-infected patients on hemodialysis (HD) have increased, and their prognostic factors are still poorly clarified. The study aimed to identify factors that can influence the survival of HIV-infected patients on HD.

Methods: We performed a retrospective cohort study of 44 HIV-infected patients on HD.

Results: A total of 17 patients (39%) died. Median survival on HD was 30.8 months and the survival rate at 1 and 5 years was 82.5 and 62.9%, respectively. Male (relative risk [RR] 3.1, p = 0.040) and blacks (RR 2.5, p = 0.037) had higher risk of death. The patients who died had a shorter duration of HIV infection (p = 0.028), had a higher viral load (p = 0.044), more opportunistic infections (p = 0.013), and a lower serum albumin (p = 0.009). Lower serum albumin, nonsexual HIV transmission, viral load, opportunistic infections, and usage of catheters were associated with lower survival.

Conclusion: Several demographic, viral, and dialysis variables may help to predict survival of this population. The intervention in these factors could improve their prognosis.

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http://dx.doi.org/10.1159/000478966DOI Listing
July 2018
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