Exposure to Direct-to-Consumer Pharmaceutical Advertising and Medication Nonadherence Among Patients With Serious Mental Illness.

Psychiatr Serv 2017 Dec 15;68(12):1299-1302. Epub 2017 Sep 15.

Ms. Green, Dr. Mojtabai, Dr. Cullen, Ms. Mitchell, and Dr. Spivak are with the Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore. Dr. Mojtabai and Dr. Cullen are also with the Bloomberg School of Public Health, Johns Hopkins University, Baltimore. Ms. Spivak is with The Samaritan Women, Baltimore.

Objective: This study explored the association of exposure to direct-to-consumer advertising (DTCA) with medication nonadherence among individuals with serious mental disorders.

Methods: Results of an anonymous survey administered at an inner-city mental health clinic were examined by using logistic regression. Nonadherence was defined as not taking prescribed medications for at least two out of seven days.

Results: Of 246 respondents, 48% reported DTCA exposure and 43% reported nonadherence. Sixty-one percent of those exposed to DTCA reported nonadherence, compared with 26% of those not exposed (adjusted odds ratio=4.96, 95% confidence interval=2.64-9.33, p<.001). Among those exposed to advertisements and reporting nonadherence, 59% reported changing medication-taking behaviors or stopping prescribed medications because of side effect information in advertisements. Only a minority communicated with providers before becoming nonadherent.

Conclusions: This study found an association between self-report of DTCA exposure and self-reported nonadherence. These results support further research on DTCA as a possible risk factor for nonadherence.

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Source
http://dx.doi.org/10.1176/appi.ps.201700035DOI Listing
December 2017
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