Artif Intell Med 2017 Oct 20;82:1-10. Epub 2017 Sep 20.
Department of Industrial Engineering - Universidade Federal do Rio Grande do Sul, Av. Osvaldo Aranha, 99-5° andar, Porto Alegre, RS, Brazil. Electronic address:
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Int J Cancer 2012 Sep 19;131(5):1153-7. Epub 2011 Nov 19.
Department of Surgical Sciences, Minimally Invasive Surgery Research Center, University of Insubria, Varese, Italy.
Colorectal cancer (CRC) screening rates are currently suboptimal. Blood-based screening could improve rates of earlier detection for CRC and adenomatous colorectal polyps. In this study, we evaluated the feasibility of plasma-based detection of early CRC and adenomatous polyps using array-mediated analysis methylation profiling of 56 genes implicated in carcinogenesis. Read More
Gastroenterology 2017 10 15;153(4):980-987. Epub 2017 Jun 15.
ATGen Canada Inc, Laval, QC, Canada.
Background & Aims: Low activity of natural killer (NK) cells has been associated with increased risk of cancer and has been reported in patients with colorectal cancer (CRC). Activity of NK cells can be measured in a small volume of whole blood by a commercially available test. We investigated whether this test could be used to identify patients with CRC, using findings from colonoscopy as a reference standard. Read More
Gastrointest Endosc 2013 Jun;77(6):858-71
Pathology Department, The Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland.
Gastrointest Endosc 2016 Mar 28;83(3):545-51. Epub 2015 Aug 28.
MD Anderson (retired), Houston, Texas, USA.
Background And Aim: Colorectal cancer (CRC) remains the second most frequent cause of cancer deaths in the United States. Blood tests using tumor-related antigens aid in diagnosing CRC. However, higher sensitivity and specificity are needed before an acceptable tumor antigen blood test for CRC is clinically useful. Read More