J Craniofac Surg 2017 Nov;28(8):e775-e776
*Şehit Kamil State Hospital, Ophthalmology Clinic, G.Antep †Department of Ophthalmology ‡Division of Pediatric Hematology, Faculty of Medicine, Mersin University §Mersin State Hospital, Ophthalmology Clinic, Mersin, Turkey.
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BMC Ophthalmol 2018 Aug 28;18(1):211. Epub 2018 Aug 28.
Department Of Ophthalmology, Faculty of Medicine, Taif University, Taif, Saudi Arabia.
Background: Sickle cell disease is a common inherited hemoglobinopathy and is associated with high morbidity and mortality. Vaso-occlusive crises commonly occur in individuals with SCD that results in high morbidity due to end-organ ischemia and infarction. These include splenic infarction, pulmonary involvement, acute chest syndrome, and orbital compression syndrome. Read More
Ann Hematol 2004 Aug 18;83(8):536-40. Epub 2004 Feb 18.
Department of Haematology, All India Institute of Medical Sciences, New Delhi, India.
Orbital compression syndrome is caused by disorders of varying etiologies involving the orbit and presents with ocular and extraocular dysfunction. Ocular involvement of sickle cell disease is uncommon. A 17-year-old male presented with low backache and proptosis of both eyes of 5 days duration without past history of pain crisis or transfusion. Read More
Ophthalmic Plast Reconstr Surg 2011 Mar-Apr;27(2):e26-7
Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
This is a case of a 2-year-old boy with sickle cell disease who presented with bilateral eyelid swelling, limited extraocular motility, and lateral subperiosteal fluid collection associated with bilateral lateral orbital wall infarctions on MRI. The patient was managed medically with intravenous fluids, analgesics, broad-spectrum antibiotics, systemic steroids, and clinically improved. Patients with sickle cell disease are susceptible to infarction of the orbital bones during vaso-occlusive crises. Read More
Ophthalmology 1997 Oct;104(10):1610-5
Department of Ophthalmology, University of Tennessee, Memphis, USA.
Background: Orbital complications are an uncommonly reported finding in sickle cell disease.
Methods: The authors review the reported orbital manifestations of sickle cell disease and discuss a patient with hemoglobin sickle beta(0) thalassemia in whom rapidly progressive bilateral orbital compression developed.
Results: Computed tomography of the orbits in a patient with fever, headache, orbital swelling, and optic nerve dysfunction displayed bilateral superior subperiosteal cystic masses. Read More