Acta Med Port 2017 08 31;30(7-8):587. Epub 2017 Aug 31.
Dermatology Department. Hospital de Santo António dos Capuchos. Centro Hospitalar de Lisboa Central. Lisboa. Portugal.
Download full-text PDF
G Ital Dermatol Venereol 2009 Apr;144(2):205-9
Dermatological Clinic, University of Catania, Polyclinic Hospital University, Catania, Italy.
Unlabelled: Genital herpes, a viral infection caused by Herpes simplex virus (HSV), is the most common cause of genital ulceration. Patients with a severe decrease in cellular immunity, such as patients positive for Human immunodeficiency virus (HIV) infection, are more likely to develop atypical, severe, disseminated and/or chronic HSV infections. On the other hand, there is an increase incidence of HIV detection among patients positive for HSV infection, as genital ulcers represent a potential portal of entry of HIV into the host. Read More
Arch Dermatol 1997 Feb;133(2):180-3
Infectious Diseases Service, State Employees Hospital of São Paulo, Brazil.
Objective: To determine the frequency of asymptomatic perianal shedding of herpes simplex virus (HSV) in adult patients with acquired immunodeficiency syndrome (AIDS).
Design: Cross-sectional study.
Setting: A 1000-bed, state-supported hospital in Brazil that provides comprehensive health care. Read More
Bull World Health Organ 2004 Jun;82(6):447-53
Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, USA.
The synergistic relationship between herpes simplex virus type 2 (HSV-2) and transmission of human immunodeficiency virus (HIV) can be substantial in developing countries that have high prevalences of both viral infections. Genital herpes, most frequently caused by HSV-2, has become the leading cause of genital ulcer disease worldwide. This review of recent research on genital herpes and enhanced susceptibility to, and transmission of, HIV is part of the "Advances in HIV/AIDS research series" which endeavours to form a bridge between the research into HIV and acquired immunodeficiency syndrome (AIDS) and the practice of HIV/AIDS prevention, care and support in developing countries. Read More
J Infect Dis 2008 Jul;198(2):241-9
Centre Muraz, Burkina Faso.
Background: Few longitudinal studies have described the interactions between reactivation of herpes simplex virus type 2 (HSV-2) infection (hereafter, "HSV-2 reactivation") and genital and systemic replication of human immunodeficiency virus type 1 (HIV-1).
Methods: Women in Burkina Faso who were seropositive for both HIV-1 and HSV-2 were enrolled in a randomized placebo-controlled trial of therapy to suppress reactivation of HSV-2 infection (hereafter, "HSV suppressive therapy"). During the baseline phase, 6 enriched cervicovaginal lavage specimens were obtained over 12 weeks to detect and quantify the HIV-1 RNA and HSV-2 DNA loads. Read More