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    Disseminated herpes simplex infection in a HIV+ patient.
    G Ital Dermatol Venereol 2009 Apr;144(2):205-9
    Dermatological Clinic, University of Catania, Polyclinic Hospital University, Catania, Italy.
    Unlabelled: Genital herpes, a viral infection caused by Herpes simplex virus (HSV), is the most common cause of genital ulceration. Patients with a severe decrease in cellular immunity, such as patients positive for Human immunodeficiency virus (HIV) infection, are more likely to develop atypical, severe, disseminated and/or chronic HSV infections. On the other hand, there is an increase incidence of HIV detection among patients positive for HSV infection, as genital ulcers represent a potential portal of entry of HIV into the host. Read More
    Asymptomatic perianal shedding of herpes simplex virus in patients with acquired immunodeficiency syndrome.
    Arch Dermatol 1997 Feb;133(2):180-3
    Infectious Diseases Service, State Employees Hospital of São Paulo, Brazil.
    Objective: To determine the frequency of asymptomatic perianal shedding of herpes simplex virus (HSV) in adult patients with acquired immunodeficiency syndrome (AIDS).

    Design: Cross-sectional study.

    Setting: A 1000-bed, state-supported hospital in Brazil that provides comprehensive health care. Read More
    Genital herpes and human immunodeficiency virus: double trouble.
    Bull World Health Organ 2004 Jun;82(6):447-53
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, USA.
    The synergistic relationship between herpes simplex virus type 2 (HSV-2) and transmission of human immunodeficiency virus (HIV) can be substantial in developing countries that have high prevalences of both viral infections. Genital herpes, most frequently caused by HSV-2, has become the leading cause of genital ulcer disease worldwide. This review of recent research on genital herpes and enhanced susceptibility to, and transmission of, HIV is part of the "Advances in HIV/AIDS research series" which endeavours to form a bridge between the research into HIV and acquired immunodeficiency syndrome (AIDS) and the practice of HIV/AIDS prevention, care and support in developing countries. Read More
    Herpes simplex virus and cytomegalovirus co-infection presenting as exuberant genital ulcer in a woman infected with human immunodeficiency virus.
    Clin Exp Dermatol 2014 Dec 23;39(8):915-7. Epub 2014 Sep 23.
    University Clinic of Dermatology, Hospital de Santa Maria, Lisbon, Portugal.
    In patients infected with human immunodeficiency virus (HIV), genital herpes can result in severe and atypical clinical presentations, and can become resistant to aciclovir treatment. Rarely, these manifestations may represent concurrent herpes simplex virus (HSV) with other agents. We report a 41-year-old black woman with HIV who presented with extensive and painful ulceration of the genitalia. Read More