Acta Med Port 2017 May 31;30(5):418-421. Epub 2017 May 31.
Serviço de Dermatologia e Venereologia. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal. Departamento de Dermatologia. Faculdade de Medicina. Universidade de Coimbra. Coimbra. Portugal.
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Med Sci Monit 2012 Sep;18(9):RA145-53
Department of Oral Surgery, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Gorlin-Goltz syndrome is a rare genetic condition showing a variable expressiveness. It is inherited in a dominant autosomal way. The strongest characteristic of the disease includes multiple basal cell carcinomas, jaw cysts, palmar and plantar pits, skeletal abnormalities and other developmental defects. Read More
Ann Univ Mariae Curie Sklodowska Med 2002 ;57(2):79-85
2nd Department of Medical Radiology, Department of Dental and Maxillofacial Radiology, Medical University of Lublin.
Gorlin-Goltz syndrome is an autosomal dominant disorder characterized by exteremly pleomorphic clinical manifestations including multiple odontogenic keratocysts. These cysts constitute only 3% to 11% of all jaw cysts, but are often of great concern to clinicians because of high recurrence rate, aggressive behavior and association with Gorlin-Goltz syndrome as they are found in 75-80% of the affected patients. In the paper there were presented histological, clinical, and radiological features of odontogenic keratocyst in Gorlin-Goltz syndrome. Read More
Ophthalmology 2001 Jun;108(6):1115-23
Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Purpose: To describe the ophthalmic and systemic features in a series of patients initially seen with eyelid basal cell carcinoma associated with Gorlin-Goltz syndrome.
Design: Retrospective noncomparative case series.
Participants: Of 105 consecutive patients with eyelid basal cell carcinoma managed at an Ocular Oncology Center between January 1973 and December 1999, four patients with Gorlin-Goltz syndrome were identified. Read More
Gen Dent 2015 Mar-Apr;63(2):e9-e12
Gorlin-Goltz syndrome is a rare hereditary disease that can have negative effects on one's quality of life. The main clinical features are multiple nevoid basal cell carcinomas, odontogenic keratocysts, congenital skeletal abnormalities, calcification of the falx cerebri, facial dysmorphism, and skin depressions (pits) on the palms and soles. Diagnosis is based on major and minor clinical and radiological criteria and can be confirmed by DNA analysis. Read More