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    Reliability and Validity of 39-Item Parkinson's Disease Questionnaire and Parkinson's Disease Quality of Life Questionnaire.

    Acta Med Port 2017 May 31;30(5):395-401. Epub 2017 May 31.
    Neurology Department. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal. Faculdade de Medicina. Universidade de Coimbra. Coimbra. Portugal.
    Introduction: Parkinson's disease has a significant impact in quality of life, which can be assessed with 39-item Parkinson's Disease Questionnaire and Parkinson's Disease Quality of Life Questionnaire. This study aimed to evaluate the reliability and validity of these scales in Portuguese patients.

    Material And Methods: Reliability was assessed through internal consistency (Cronbach's alpha) and reproducibility (intraclass correlation coefficient). Regarding construct validity, we performed one-way analysis of variance across different groups according to modified Hoehn and Yahr scale. For criterion validity, we compared both scales with each other and with the Short Form 36-item Health Survey.

    Results: In a total of 100 patients with Parkinson's disease, Cronbach's alpha ranged for 39-item Parkinson's Disease Questionnaire between 0.66 - 0.98, and for Parkinson's Disease Quality of Life Questionnaire, between 0.78 - 0.98. Intraclass correlation coefficient for 39-item Parkinson's Disease Questionnaire ranged between 0.49 - 0.96, and for Parkinson's Disease Quality of Life Questionnaire, ranged between 0.65 - 0.96. Both scales showed, in general, capacity to discriminate differences among patients in the different stages of disease. The scales presented moderate to strong magnitude correlations with some Short Form 36-item Health Survey domains.

    Discussion: Cronbach's alpha coefficients for most domains were satisfactory. Overall, it has been demonstrated good reproducibility, as well as construct and criterion validity.

    Conclusion: The Portuguese versions of both scales showed to be valid and reliable.
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