Zhonghua Jie He He Hu Xi Za Zhi 2017 Aug;40(8):604-610
Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
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Am J Surg Pathol 1999 Jan;23(1):17-26
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Erdheim-Chester disease is a clinicopathologic entity defined by a characteristic pattern of symmetric osteosclerosis caused by an infiltrate of mononuclear cells that include prominent numbers of foamy histiocytes. About half of patients have extraskeletal manifestations, including involvement of the hypothalamus/posterior pituitary, orbit, retroperitoneum, skin, lung, and heart. Pulmonary involvement is an uncommon but important manifestation of Erdheim-Chester disease because it causes significant morbidity and mortality. Read More
Zhonghua Bing Li Xue Za Zhi 2014 Dec;43(12):809-13
Objective: To explore the clinicopathologic features, immunophenotype, differential diagnosis and gene mutation status of the Erdheim-Chester disease (ECD).
Methods: Clinical and pathologic findings of 3 ECD cases were examined by gross, microscopic, immunohistochemical methods and BRAF V600E mutation. Related literatures were reviewed. Read More
Hell J Nucl Med 2011 Sep-Dec;14(3):311-2
Nuclear Medicine Unit-Di.M.I.M.P., University of Bari, Piazza G. Cesare, 11, 70124 Bari, Italy.
Erdheim-Chester disease (ECD), first described by Jakob Erdheim and William Chester in 1930, is a rare form of non-Langerhan's cell histiocytosis with unknown aetiology, is charaterized by systemic xanthogranulomatous infiltrative disease. To date, about 350 cases of ECD have been described in the medical literature. The typical ECD diagnostic triad is bone pain, diabetes insipidus and bilateral exophthalmos. Read More
AJR Am J Roentgenol 2000 May;174(5):1327-31
Department of Diagnostic Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Objective: We determined the chest radiographic and CT findings of Erdheim-Chester disease with pulmonary involvement.
Materials And Methods: We retrospectively reviewed the radiologic images of 15 patients with biopsy-proven Erdheim-Chester disease. Nine patients had chest radiographic images and CT scans that were available for review. Read More