BMJ Open 2017 Aug 3;7(8):e017406. Epub 2017 Aug 3.
Division of Psychiatry, University College London, London, UK.
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BMJ 2015 Sep 1;351:h4326. Epub 2015 Sep 1.
Research Department of Primary Care and Population Health, University College London (Royal Free Campus), London NW3 2PF, UK.
Objectives: To describe the incidence of recorded mental illness and challenging behaviour in people with intellectual disability in UK primary care and to explore the prescription of psychotropic drugs in this group.
Design: Cohort study.
Setting: 571 general practices contributing data to The Health Improvement Network clinical database. Read More
BMJ Open 2016 12 5;6(12):e013116. Epub 2016 Dec 5.
Imperial College, London, UK.
Objectives: To determine the prevalence and quality of antipsychotic prescribing for people with intellectual disability (ID).
Design: A clinical audit of prescribing practice in the context of a quality improvement programme. Practice standards for audit were derived from relevant, evidence-based guidelines, including NICE. Read More
J Clin Psychopharmacol 2016 Aug;36(4):308-13
From the *Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht; †Altrecht Institute for Mental Health Care, Den Dolder; ‡Licht-Zorg, Psychiatric Care, Maarssen; §Behavioural Science Institute, Faculty of Social Sciences, Radboud University Nijmegen, Nijmegen; ∥GGZ Centraal, Department Innova, Amersfoort; and ¶Department of Clinical Pharmacy, University Medical Centre Utrecht, Utrecht, the Netherlands.
Background: Antipsychotic drugs are prescribed to approximately 30% to 40% of adults with intellectual disability (ID) and behavioral problems despite lack of evidence of effectiveness and potential adverse effects, including movement disorders.
Aims: The aim of this study was to examine the prevalence of movement disorders (dyskinesia, akathisia, dystonia, and parkinsonism) in in-patient adults with mild to borderline ID and behavioral problems associated with use of antipsychotics.
Methods: Prevalence of movement disorders was measured with a standardized protocol. Read More
Am J Psychiatry 1991 Oct;148(10):1322-8
Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY 10962.
Objective: The authors' goal was to determine the prevalence of and risk factors for neuroleptic-induced movement disorders in a group of psychiatrically hospitalized children and adolescents.
Method: They evaluated the presence or absence of parkinsonism, tardive dyskinesia, and akathisia in 104 children and adolescents who were in residence in or admitted over a 6-month period to a state-operated child psychiatric center. They applied a standardized, structured assessment procedure used in research on adult and geriatric psychiatric patients and the mentally retarded. Read More