ACS Appl Mater Interfaces 2017 Aug 15;9(33):27544-27552. Epub 2017 Aug 15.
Manchester Institute of Biotechnology, University of Manchester , 131 Princess Street, Manchester, M1 7DN, U.K.
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J Biol Buccale 1976 Dec;4(4):323-30
A comparative study of the dissolution of synthetic hydroxyapatite and human enamel crystals has been realized in a buffered (sodium citrate - citric acid) solution in presence of variable quantities of sodium fluoride. The pH of the solutions used was 3.7 and 5. Read More
Caries Res 2008 19;42(5):348-53. Epub 2008 Aug 19.
Department of Oral and Dental Science, University of Bristol, Bristol, UK.
Hydroxyapatite is the main constituent of the dental hard tissues, and in vivo its dissolution in acids leads to the pathological condition of dental erosion. Food proteins which inhibit hydroxyapatite dissolution may find application as erosion-reducing agents in food and drink products. The aim of this study was to investigate the egg protein ovalbumin as a potential inhibitor of hydroxyapatite dissolution in acidic solutions, with conditions representative of dental erosion. Read More
Calcif Tissue Int 1990 Feb;46(2):121-9
C.T.R. Odontologiques, Inserm U-157, CNRS UA-105, Strasbourg, France.
The kinetics of dissolution of synthetic hydroxyapatite powder (HAP) were studied at 37 degrees C and constant pH in the pH range 3.7-6.9 by continuously recording proton uptake and calcium release. Read More
Am J Pathol 1988 Oct;133(1):22-9
Department of Biochemistry, Hospital For Special Surgery, New York, New York 10021.
The deposition of calcium-containing crystals in tissues is due to a combination of factors: elevation in the concentrations of precipitating ions, formation of specific nucleators, and removal of macromolecules that inhibit crystal deposition. This study tested the hypothesis that calcium acidic phospholipid phosphate complexes, which promote hydroxyapatite deposition both in vitro and in vivo, are associated only with hydroxyapatite deposits, and furthermore, that the presence of these complexes is associated with all such hydroxyapatite deposits. Lipid analysis of 76 surgical specimens containing evidence of pathologic calcification (35 hydroxyapatite, 35 calcium pyrophosphate dihydrate, and 6 containing other crystalline materials) had mean complexed acidic phospholipid contents of 8. Read More