Oxidation-induced C-H amination leads to a new avenue to build C-N bonds.

Chem Commun (Camb) 2017 Aug;53(64):8984-8987

College of Chemistry and Molecular Sciences, the Institute for Advanced Studies, Wuhan University, Wuhan, Hubei 430072, People's Republic of China.

In this work, we develop an oxidation-induced C-H functionalization strategy, which not only leads to a new avenue to build C-N bonds, but also leads to different site-selectivity compared with "classic directing-groups". The high selectivity of our new catalytic system originates from the heterogeneous electron-density distribution of the radical cation species which are induced by single electron transfer between the aromatics and oxidant-Cu(ii) species.

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http://dx.doi.org/10.1039/c7cc04955bDOI Listing
August 2017
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References

(Supplied by CrossRef)

Liu et al.
Chem. Rev. 2015

Liu et al.
Chem. Rev. 2011

Wu et al.
Acc. Chem. Res. 2014

Arockiam et al.
Chem. Rev. 2012

Colby et al.
Chem. Rev. 2009

Lyons et al.
Chem. Rev. 2010

Lersch et al.
Chem. Rev. 2005

Zaitsev et al.
J. Am. Chem. Soc. 2005

Wang et al.
J. Am. Chem. Soc. 2010

Gandeepan et al.
J. Am. Chem. Soc. 2012

Simmons et al.
Nature 2012

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