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Institutional Oversight of Occupational Health and Safety for Research Programs Involving Biohazards.

Authors:
Melissa C Dyson Calvin B Carpenter Lesley A Colby

Comp Med 2017 Jun;67(3):192-202

Department of Comparative Medicine, University of Washington, Seattle, Washington.

Research with hazardous biologic materials (biohazards) is essential to the progress of medicine and science. The field of microbiology has rapidly advanced over the years, partially due to the development of new scientific methods such as recombinant DNA technology, synthetic biology, viral vectors, and the use of genetically modified animals. This research poses a potential risk to personnel as well as the public and the environment. Institutions must have appropriate oversight and take appropriate steps to mitigate the risks of working with these biologic hazards. This article will review responsibilities for institutional oversight of occupational health and safety for research involving biologic hazards.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482511PMC
June 2017

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The current study was designed to provide a preliminary physico-chemical characterization of zein nanosystems prepared with various Brij surfactants (for the first time to the best of our knowledge) as a function of various external stimuli such as temperature, pH, serum incubation and the freeze-drying process. The results demonstrate that when Brijs are characterized by unsaturation (C18), considerable stabilization of the colloidal structure is promoted while the length of the polyethylene glycol fraction does not significantly modulate the physico-chemical properties of the nanosystems. Specifically, dynamic light scattering and nanoparticle tracking analysis demonstrated that the use of 0. Read More

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Eur J Pharm Biopharm 2021 Feb 24. Epub 2021 Feb 24.

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