[Evaluation of a seminal vesicle biopsy protocol simultaneous to diagnostic prostate biopsy. Analysis of indication criteria.]

Arch Esp Urol 2017 Jun;70(5):493-502

Departamento de Urología. Hospital General Universitario JM Morales Meseguer. Murcia. España.

Objectives: To analyze the indication criteria used for conducting seminal vesicles biopsies as well as the diagnostic capacity of other variables involved.

Methods: We present the results of an observational and retrospective study (May 2006 - December 2012) using a sample of 140 patients to whom seminal vesicles biopsies was performed in a first set of prostate biopsy. They were patients eligible for curative treatment and presented any of the following criteria: PSA ≥15 ng/ml, suspicion of neoplastic seminal vesicle invasion on transrectal US, and/or suspicious node in the prostate base on DRE or transrectal US.

Results: Seminal vesicle invasion due to prostate cancer was detected in 22.2%. Patients with 3 criteria had T3b in 66.7% of cases. The criterion most associated with T3b was the presence of a suspicious node in the prostate base, with an association of 29.3% of cases. Variables analyzed that had shown a greater association with stage T3b were PSA density, the presence of suspicious DRE, the Gleason sum.

Conclusions: Our seminal vesicle biopsy protocol has detected 22.2% of seminal vesicle invasion. The detection of a suspicious node at the prostate base has shown the greatest association with T3b.
June 2017
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