Scleroderma-like Disorders.

Authors:
Amit Sharma
Amit Sharma
Molecular Medicine Group
Sacramento | United States

Curr Rheumatol Rev 2018 Apr;14(1):22-27

Fortis Escorts Hospital, Jaipur, Rajasthan, India.

Background: Scleroderma is a term used to describe diseases that involve hardening and tightening of the skin and the underlying subcutaneous connective tissue. It could be localized to skin and subcutaneous tissue, or may involve the internal organs too in systemic sclerosis.

Objective: There are disorders that can cause hardening and tightening of skin and mimic scleroderma but are rarely associated with Raynaud phenomenon, sclerodactyly, and autoantibodies in the serum, features specific to scleroderma/systemic sclerosis.

Conclusion: These are termed as "scleroderma variants" or "scleroderma like disorders". This review discusses the various "scleroderma variants" e.g. scleromyxedema, scleredema, nephrogenic systemic fibrosis, and eosinophilic fasciitis.

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http://dx.doi.org/10.2174/1573397113666170612091419DOI Listing

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April 2018
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