Case Rep Pediatr 2017 11;2017:4836142. Epub 2017 May 11.
Department of Pediatrics, Universal College of Medical Sciences, Bhairahawa 32900, Nepal.
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Cutis 2013 Aug;92(2):83-7
Department of Dermatology, University of Alabama at Birmingham, 1530 3rd Ave S, EFH Set 414, Birmingham, AL 35294-0009, USA.
Sclerema neonatorum (SN) is a rare neonatal panniculitis that typically develops in severely ill, preterm newborns within the first week of life and often is fatal. It usually occurs in preterm newborns with delivery complications such as respiratory distress or maternal complications such as eclampsia. Few clinical trials have been performed to address potential treatments. Read More
Pediatr Infect Dis J 2009 May;28(5):435-8
Department of International Health, International Center for Advancing Neonatal Health, Johns Hopkins University, Baltimore, MD, USA.
Background: This study presents a retrospective analysis of risk factors for sclerema neonatorum in preterm neonates in Bangladesh.
Methods: Preterm neonates admitted to Dhaka Shishu Hospital in Bangladesh were enrolled in a clinical trial to evaluate the effects of topical treatment with skin barrier-enhancing emollients on prevention of sepsis and mortality. Four hundred ninety-seven neonates were enrolled in the study and 51 (10. Read More
J Perinatol 2008 Jul 27;28(7):453-60. Epub 2008 Mar 27.
Department of International Health, International Center for Advancing Neonatal Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Objective: To review published literature on sclerema neonatorum (SN) in order to clarify its clinical presentation, histological features and management compared with two other diseases: subcutaneous fat necrosis of the newborn (SCFN) and scleredema.
Study Design: PubMed database was searched using the key words Sclerema neonatorum. A total of 55 articles from peer-reviewed journals were reviewed and summarized. Read More
Arch Dis Child 1975 Nov;50(11):901-2
Two critically ill newborn babies with severe infection associated with sclerema were successfully treated with appropriate antibiotics and repeated exchange transfusions. Read More