Drug-class-specific changes in the volume and cost of antidiabetic medications in Poland between 2012 and 2015.

PLoS One 2017 5;12(6):e0178764. Epub 2017 Jun 5.

Jan Kochanowski University in Kielce, Kielce, Poland.

Aim: to investigate the drug-class-specific changes in the volume and cost of antidiabetic medications in Poland in 2012-2015.

Methods: This retrospective analysis was conducted based on the National Health Fund database covering an entire Polish population. The volume of antidiabetic medications is reported according to ATC/DDD methodology, costs-in current international dollars, based on purchasing power parity.

Results: During a 4-year observational period the number of patients, consumption of antidiabetic drugs and costs increased by 17%, 21% and 20%, respectively. Biguanides are the basic diabetes medication with a 39% market share. The insulin market is still dominated by human insulins, new antidiabetics (incretins, thiazolidinediones) are practically absent. Insulins had the largest share in diabetes medications expenditures (67% in 2015). The increase in antidiabetic medications costs over the analysed period of time was mainly caused by the increased use of insulin analogues.

Conclusions: The observed tendencies correspond to the evidence-based HTA recommendations. The reimbursement status, the ratio of cost to clinical outcomes and data on the long-term safety have a deciding impact on how a drug is used.

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Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178764PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459444PMC
September 2017
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