Arch Plast Surg 2017 May 22;44(3):194-201. Epub 2017 May 22.
Department of Plastic and Reconstructive Surgery, Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
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J Artif Organs 2015 Mar 18;18(1):64-71. Epub 2014 Oct 18.
Department of Plastic and Reconstructive Surgery, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan,
Platelet-rich plasma (PRP) contains numerous growth factors to promote wound healing and angiogenesis. The objective of this study was to explore the efficacy of biodegradable gelatin hydrogel impregnated with PRP releasate (PRPr) in the wound healing process compared with the single application of PRPr prepared from mouse PRP centrifuged by a double-spin method. Gelatin hydrogel disks with an isoelectric point of 5. Read More
Int J Mol Sci 2016 Jun 24;17(7). Epub 2016 Jun 24.
Department of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai 200233, China.
Traditional therapeutic methods for skin wounds have many disadvantages, and new wound dressings that can facilitate the healing process are thus urgently needed. Platelet-rich plasma (PRP) contains multiple growth factors (GFs) and shows a significant capacity to heal soft tissue wounds. However, these GFs have a short half-life and deactivate rapidly; we therefore need a sustained delivery system to overcome this shortcoming. Read More
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 Jun;32(6):726-735
Department of Burns and Plastic Surgery, the Affiliated Hospital of Zunyi Medical College, Zunyi Guizhou, 563003,
Objective: To investigate the effect of human adipose-derived stem cells (hADSCs) on pressure ulcers in mouse.
Methods: The subcutaneous adipose tissue from voluntary donation was harvested. Then the hADSCs were isolated and cultured by mechanical isolation combined with typeⅠcollagenase digestion. Read More
Bull Emerg Trauma 2016 Jan;4(1):29-37
Department of Mechanical Engineering of Biosystems, Faculty of Agriculture, Urmia University, Urmia, Iran.
Objective: To assess the effects of platelet rich plasma (PRP) with chitosan biodegradable film on full thickness wound healing in rat.
Methods: This was an experimental study being performed in 2015 during a 4-month period. Twenty-four male white Wistar rats were divided into four groups of 12 rats each, randomly: Control group (SHAM) with creation of wounds and no treatment, PRP group with creation of wounds and application of one milliliter PRP, Chitosan group (CHIT) with dressing the wound with chitosan and CHIT/PRP group with application of one mL PRPand dressing the wound with chitosan. Read More